Publications by authors named "Thomsen T"

Aim/objective: Iatrogenic withdrawal syndrome occurs frequently during the tapering phase of opioids and benzodiazepines in paediatric intensive care units. The aim of this study was to explore physicians' and nurses' experiences in patient care and staff collaboration during the tapering phase using a new "algorithm for tapering analgosedation" METHODS: We used a qualitative explorative design with focus groups. The framework method was followed including transcription, familiarisation, coding, developing a framework, applying the framework, charting data into the framework matrix, and interpreting the data.

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  • * A scoping review analyzed 53 studies from 2001-2024, showing CPSP prevalence ranges from 3.3% to 46.1%, with only half the studies defining CPSP clearly and inconsistent pain assessment methods.
  • * There's a need for standardized definitions and methodologies in future research to better understand CPSP, especially focused on specific surgical procedures to improve prevention and treatment strategies.
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Background: Due to genetic depletion in nature, gene banks play a critical role in the long-term conservation of plant genetic resources and the provision of a wide range of plant genetic diversity for research and breeding programs. Genetic information on accessions facilitates gene bank management and can help to conserve limited resources and to identify taxonomic misclassifications or mislabelling. Here, we developed SNP markers for genotyping 4,187 mostly polyploid rose accessions from large rose collections, including the German Genebank for Roses.

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  • Wearable technologies like inertial measurement units (IMUs) can assess human gait, but fixing the sensors in place is a challenge that must be addressed.
  • This study developed a machine learning algorithm using a single IMU, simulating smartphone use, to predict key gait events while participants walked at various speeds.
  • The method achieved 92% overall accuracy in detecting heel strikes and toe-offs, with promising results for potential future applications in remote gait analysis without the need for sensor fixation.
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Background: Decision-making and problem-solving processes are powerful activities occurring daily across all healthcare settings. Their empowering potential is seldom fully exploited, and they may even be perceived as disempowering. We developed the EMPOWER-UP questionnaire to enable assessment of healthcare users' perception of empowerment across health conditions, healthcare settings, and healthcare providers' professional backgrounds.

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Background: In the intensive care unit (ICU), delirium in patients and long-term mental health challenges in both patients and their family members are highly prevalent. To address these issues, patient- and family-centered care has been recommended to alleviate the burdens associated with critical illness and ICU admission. We have developed the patient- and FAMily-centered care in the adult ICU intervention (FAM-ICU intervention).

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  • The study aimed to understand what patients prioritize on the day of their surgery and to showcase the effectiveness of a flash mob research method in a perioperative context.
  • Conducted in Danish surgical units, the study involved adult patients who shared their concerns about safety, information, and care, with many feeling their needs were overlooked by staff.
  • The findings highlighted the importance of proactive communication from healthcare professionals to better address patient needs and improve the surgical experience.
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Background: Adequate nutrition is important for recovery after critical illness. Even so, our knowledge of patients' nutritional intake after intensive care unit (ICU) discharge is scarce.

Objectives: We aimed to explore nutritional planning and achieved nutritional intake in ICU patients who transfer from the ICU to general wards.

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Introduction: Fatigue often leads to a sedentary lifestyle, negatively impacting health, mortality, and quality of life. Engaging in physical activity can be challenging for individuals experiencing fatigue, particularly those with sleep apnea. This study's objective was to assess the "First Step" concepts' usability in constructing and implementing different interventions through qualitative data.

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Purpose: To establish consensus between intensive care unit (ICU) experts on concrete patient- and family-centered care statements for adult patients and relatives in the ICU.

Materials And Methods: We did a three-round Delphi survey with a panel of ICU health care professionals from 23 ICUs in Denmark. In round 1, participants answered 20 open-ended questions, based on existing evidence.

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Background: Delirium is an acute and fluctuating disturbance in attention, awareness, and cognition, commonly observed in hospital settings, particularly among older adults, critically ill and surgical patients. Delirium poses significant challenges in patient care, leading to increased morbidity, mortality, prolonged hospital stays, and functional decline.

Aim: The aim of this review is to map existing evidence on delirium diagnostic tools suitable for use in patients treated surgically due to hip fracture, to inform clinical practice and enhance patient care protocols in the postoperative setting.

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  • A 21-year-old African American female sprinter experienced right foot pain, fatigue, and an unusual continuous menstrual cycle despite a contraceptive implant for three years.
  • An MRI revealed a likely stress fracture in her foot and abnormal bone marrow signals, leading to further investigation after ongoing pain.
  • The results showed severely high triglyceride levels and diabetes, indicating a rare congenital lipodystrophy that initially appeared as a stress fracture and unusual menstrual issues.
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  • The study investigates the phenomenon of non-return to work (non-RTW) among patients with Ischemic Heart Disease (IHD) over a year following their hospital discharge.
  • It uses data from a national study that included 3,873 IHD patients who reported their mental and physical health through various assessment scales.
  • Results show that about 38% of patients did not return to work after 12 months, with STEMI patients at the highest risk, indicating the importance of monitoring and supporting these individuals post-discharge to enhance their chances of returning to work.
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Introduction: High quality of early stroke care is essential for optimizing the chance of a good patient outcome. The quality of care may be monitored by process performance measures (PPMs) and previous studies have found an association between fulfilment of PPMs and short-term mortality. However, the association with long-term mortality remains to be determined.

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Background: Testing and titration of the right levodopa equivalent dose are usually performed during a hospital admission. However, optimal dose titration in people with Parkinson's disease (PwPs) may depend on home environment, emotional stress, and physical activity of everyday life.

Objective: Firstly, to evaluate the feasibility and safety of a home-based LCIG titration program and patients'/caregivers' satisfaction.

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When newly diagnosed with inflammatory arthritis (IA), acquiring self-management skills is beneficial, to enhance quality of life. The personal beliefs and mental representations patients hold about their illness, known as illness perception, significantly influence the development of these skills. Recognizing characteristics that affect illness perception is key to identifying patients requiring additional support for the development of self-management skills.

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Objective: To compare the effectiveness, compliance, and side effect profile between daily or three times weekly (TIW) oral iron supplementation regimens in treating iron deficiency nonanemia (IDNA) in National Collegiate Athletic Association (NCAA) Division 1 female track and field or soccer athletes.

Design: Prospective cohort study.

Setting: Division 1 collegiate athletics.

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Background: Chronic postsurgical pain (CPSP) presents a considerable healthcare challenge, impacting patients, and healthcare providers, particularly in the context of gastrointestinal surgery. The notable incidence of CPSP in this specific surgical domain emphasizes the need to identify patients with a high risk of developing this condition. Despite various studies exploring this topic, a comprehensive systematic review focusing on prognostic factors of CPSP following gastrointestinal surgery is currently lacking.

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  • Supplementing one-carbon metabolism micronutrients like B-vitamins and methionine is crucial for the growth of Atlantic salmon, especially with the shift to non-fish meal diets in aquaculture.
  • The study investigated the effects of different levels of these nutrients on gene expression and DNA methylation through RNA sequencing and reduced-representation bisulfite sequencing.
  • Results showed that varying dosages of one-carbon nutrients significantly influenced genetic and epigenetic regulation in the liver, particularly in pathways related to protein synthesis, highlighting their role in growth performance.
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Background: Within Parkinson's disease (PD) management, a pivotal juncture often arises when individuals with PD (PwP) necessitate advanced therapies to stabilise symptom fluctuations and reduce off-periods, which are intrinsic to living with PD. One such intervention is the infusion of duodenal levodopa-entacapone-carbidopa intestinal gel (LECIG), which confers a more dependable levodopa plasma concentration compared with conventional oral therapy. It involves the insertion of a percutaneous endoscopic gastrojejunostomy (PEG-J) tube, facilitating direct access to the stomach and jejunum.

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Biocatalytic degradation of plastic waste is anticipated to play an important role in future recycling systems. However, enzymatic degradation of crystalline poly (ethylene terephthalate) (PET) remains consistently poor. Herein, we employed functional assays to elucidate the molecular underpinnings of this limitation.

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The diagnosis or rare mesenchymal malignant lesions of the liver may be a challenge owing to the rarity of the disease and is usually made by histological confirmation. An ultrasound examination with, if required, color Doppler sonography and contrast-enhanced ultrasound, taking into account the clinical background of the patient, may help to focus the differential diagnosis. In this review, we describe the pathological and ultrasound features of several rare mesenchymal malignant liver lesions which include undifferentiated sarcoma of the liver, leiomyosarcoma, angiosarcoma, fibrosarcoma, liposarcoma, and epithelioid hemangioendothelioma.

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  • * This scoping review aims to analyze existing studies on CPSP related to gastrointestinal surgery by looking into its prevalence, risk factors, and effects on quality of life, while excluding hernia surgeries.
  • * The review will adhere to PRISMA guidelines and will present findings through a narrative summary and descriptive statistics, helping to identify research gaps for future studies on CPSP.
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Increased plastic recycling is necessary to reduce environmental impacts related to manufacturing and end-of-life of plastic products, however, mechanical recycling (MR) - currently the most widespread recycling option for plastic waste - is limited by quality requirements for inputs and reduced quality of outputs. In this study, pyrolysis of plastic waste is assessed against MR, municipal solid waste incineration (MSWI) and fuel substitution through climate footprint assessment (CFA) based on primary data from pyrolysis of plastic waste sourced from Danish waste producers. Results of the CFA are scaled to the Danish plastic waste resource in an impact assessment of current Danish plastic waste management, and scenarios are constructed to assess reductions through utilization of pyrolysis.

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