Morphological and cellular changes in secondary epidermal laminae of horses with insulin-induced laminitis.

Objective: To determine cellular changes associated with secondary epidermal laminae (SEL) in forefeet and hind feet of ponies with insulin-induced laminitis.

Animals: 8 ponies.

Procedures: Laminitis was induced in 4 ponies by IV administration of insulin and glucose; 4 control ponies received saline (0.