Publications by authors named "Thomas V Gerstner"
Background: While the impacts of atopic dermatitis (AD) on maternal and child sleep outcomes have been previously explored, less is known about the associations between infantile AD and sleep quality and quantity.
Objective: To describe the perceived causes of AD-associated maternal sleep disturbances and the association between AD severity and infant sleep outcomes.
Methods: Mothers with infants aged < 19 months old with a diagnosis of AD were recruited from social media and medical clinics in Winnipeg, Canada between October 2021 and May 2022.
Infantile atopic dermatitis and maternal-infant bonding: a mixed methods study.
Allergy Asthma Clin Immunol
November 2023
Background: Childhood atopic dermatitis can have a negative effect on caregivers' quality of life and stress levels due to the burdensome nature of its treatment. Given that the condition often emerges in infancy, atopic dermatitis-related stress also carries the potential to negatively affect the developing mother-infant bond. While it is plausible that atopic dermatitis has a negative impact on maternal-infant bonding, these relationships have not been studied directly.
View Article and Find Full Text PDFRisk factors associated with safety of preschool peanut oral immunotherapy.
J Allergy Clin Immunol Glob
May 2023
Article Synopsis
- The study investigates how patient characteristics like age, initial reactions, and specific IgE levels influence safety outcomes during peanut oral immunotherapy (P-OIT), aimed at improving decision-making between clinicians and families.
- Data from the Food Allergy Immunotherapy (FAIT) registry were analyzed, revealing that certain factors, including previous reactions and higher IgE levels, are linked to more severe reactions during treatment.
- Key findings emphasize the importance of individualized risk assessment for patients undergoing P-OIT to ensure safer therapeutic outcomes.
First Real-World Effectiveness Analysis of Preschool Peanut Oral Immunotherapy.
J Allergy Clin Immunol Pract
March 2021
Article Synopsis
- A study examined the safety and effectiveness of peanut oral immunotherapy (P-OIT) for preschoolers, noting that only a small percentage (0.4%) experienced severe reactions during the treatment period.
- After one year of P-OIT maintenance, 78.6% of participants showed successful desensitization, indicating a negative follow-up oral food challenge (OFC), while the majority tolerated high doses of peanuts.
- The findings suggest that P-OIT is an effective option for preschoolers with peanut allergies, as it increases their tolerance and offers a potential alternative to strict peanut avoidance.
First Real-World Safety Analysis of Preschool Peanut Oral Immunotherapy.
J Allergy Clin Immunol Pract
October 2020
Article Synopsis
- - In a 2017 trial, preschool peanut oral immunotherapy (P-OIT) was deemed safe, with mostly mild reactions and only 1 moderate case needing epinephrine.
- - A follow-up study in Canada involved 270 preschool children receiving P-OIT, where 243 reached the maintenance dose over 16 to 22 weeks, and 67.8% experienced some reactions, primarily mild.
- - The results suggest that while P-OIT is safe for most children, a small percentage (0.4%) may still experience severe reactions, highlighting the need for caution.
Allergy to cooked, but not raw, peas: a case series and review.
Allergy Asthma Clin Immunol
March 2015
Allergic reactions to legumes are common.Food allergy to cooked, but not raw, pea has been rarely reported in the literature. This case series describes five children who had various IgE-mediated symptoms upon consumption of cooked pea, but tolerated raw pea.
View Article and Find Full Text PDFAnaphylaxis to avocado, independent of latex sensitization, has been rarely reported in the literature. This case report describes a 15 year old male who experienced anaphylaxis within half an hour after eating avocado-containing food. Avocado consumption is common in both North America and South America.
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