A case report of a family with 7 patients of the Von Hippel-Lindau disease.

Background: This study presents a family with hereditary cerebellar hemangioblastomas, as manifestations of the VHLD.

Methods: In a 20-year period, 7 members of a family, in 3 generations, developed symptoms of the VHLD with very high frequency and gene penetration. Six patients were operated for cerebellar hemangioblastomas.