Publications by authors named "Thomas S T Lai"

Article Synopsis
  • Chronic hepatitis C genotype 6 is prevalent in Hong Kong, particularly among intravenous drug users, and past treatment responses have varied greatly among small study groups.
  • A study involving 70 patients compared the effectiveness of pegylated interferon and ribavirin in treating genotype 6 versus genotype 1.
  • Results showed genotype 6 patients had significantly better early and sustained virological responses, indicating they respond more favorably to treatment than those with genotype 1.
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Severe acute respiratory syndrome (SARS) is a novel coronavirus infection which broke out in Hong Kong in March 2003. Princess Margaret Hospital was designated to manage this new, mysterious and serious disease. Healthcare workers had to work under extremely stressful and often risky conditions to care for patients.

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We recruited 688 hospital healthcare workers who cared for patients with severe acute respiratory syndrome (SARS) and did not develop the disease in the Hong Kong outbreak in 2003. A questionnaire survey was conducted and serum samples were collected for SARS-associated coronavirus (SARS-CoV) antibody. The high-risk procedures performed and the types of unprotected exposures were recorded for analysis.

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Background: Severe acute respiratory syndrome (SARS) is a newly emerged infection from a novel coronavirus (SARS-CoV). Apart from fever and respiratory complications, acute renal impairment has been observed in some patients with SARS. Herein, we describe the clinical, pathologic, and laboratory features of the acute renal impairment complicating this new viral infection.

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