Publications by authors named "Thomas S Nakuz"

Background: Interstitial lung disease (ILD) is a common manifestation of idiopathic inflammatory myopathies (IIM) and a substantial contributor to hospitalisation, increased morbidity, and mortality. In-vivo evidence of ongoing tissue remodelling in IIM-ILD is scarce. We aimed to evaluate fibroblast activation in lungs of IIM-patients and control individuals using ⁶⁸Ga-labelled inhibitor of Fibroblast-Activation-Protein (FAPi) based positronic emission tomography and computed tomography imaging (PET/CT).

View Article and Find Full Text PDF
Article Synopsis
  • This study explored the effectiveness of ensemble learning models for detecting breast cancer characteristics using [F]FDG-PET/CT images, with and without pre-processing protocols.
  • A cohort of 170 patients provided data on 173 tumors, and specialized techniques were applied to enhance the extraction of relevant features and address data quality issues.
  • Results indicated strong performance in detecting breast cancer and identifying aggressive triple negative tumors, though models for individual receptor status and specific subtypes showed lower effectiveness.
View Article and Find Full Text PDF

Background: The objective of this study was to characterize tumor activity and mineralization status in newly-detected multiple myeloma (MM) bone lesions using 2-F-fluoro-2-deoxy-D-glucose (F-FDG)-PET/CT and F-sodium fluoride (F-NaF)-PET/CT before and after antitumor treatment.

Materials And Methods: In this retrospective study, seven patients with histologically-verified MM were included (four women, three men; median age=57 years, standard deviation=11.23 years).

View Article and Find Full Text PDF

Aim: We evaluated the clinical usefulness of 6-[F]fluoro-3,4-dihydroxy-L-phenylalanine(F-FDOPA)-positron-emission tomography (PET)/computed tomography (CT) in insulinoma detection with contrast enhancement, early acquisition time, and no carbidopa premedication.

Patients And Methods: Twenty-six patients diagnosed with hyperinsulinemic hypoglycemia underwent an F-FDOPA PET/CT examination. Patients without carbidopa premedication and contrast-enhanced CT were included.

View Article and Find Full Text PDF