Insulin and IGF-2 support rat corneal endothelial cell growth and wound repair in the organ cultured tissue.

The ability of insulin and IGF-2 to support wound repair in the organ-cultured rat corneal endothelium was investigated. Corneas given a circular transcorneal freeze injury, were explanted into organ cultures containing either insulin or IGF-2 and cultured up to72 h. Both factors increased [H]-thymidine incorporation and mitotic levels compared to controls.

Unicompartmental knee arthroplasty: 3- to 10-year results in a community hospital setting.

The results of 40 medial unicompartmental knee arthroplasties, performed by a single surgeon in a community hospital setting, with an average follow-up of 6 years (range, 3-10 years), were analyzed retrospectively. The Knee Society rating system was used, revealing an average score of 80.5 points and 79% good-to-excellent results.