Publications by authors named "Thomas P Swope"
Article Synopsis
- DNA experiences high mechanical stress from bending and twisting in various biological structures, such as nucleosomes and virus capsids, affecting essential processes like packaging and gene regulation.
- A new ligation assay developed on nicked DNA circles shows that DNA can unwind to over 11 base pairs per turn when curving tightly, challenging the conventional belief that its helical structure remains consistent.
- This research necessitates a re-evaluation of DNA's mechanical model and its implications for molecular processes involving tightly bent DNA.
