Metastatic cutaneous Crohn disease is a rare entity with an uncertain etiology. Few cases of facial involvement have been reported. We describe a 45-year-old woman who presented with several large, dusky, erythematous plaques and draining sinuses on her cheeks in the setting of chronic intestinal Crohn disease.
View Article and Find Full Text PDFToxic epidermal necrolysis (TEN) is a severe, mucocutaneous, necrolytic reaction to a variety of antigenic stimuli. The use of systemic corticosteroids in the treatment of TEN is controversial because of a lack of randomized, controlled, prospective studies, and because the effects of steroid therapy vary depending on the dosage and time of its administration during the course of TEN. Immediate intervention is crucial, and the response to corticosteroids in early-stage TEN can be difficult to clinically assess.
View Article and Find Full Text PDFEpithelioid sarcoma is a rare, highgrade, soft tissue tumor that has a known propensity for local recurrence, regional lymph node involvement, and distant metastases. We review the clinical and histological presentations of epithelioid sarcoma. Because epithelioid sarcoma presents innocuously, it is often mistaken as a benign process, which can result in insufficient treatment.
View Article and Find Full Text PDFBackground: Kaposi's varicelliform eruption (KVE), first described in 1887 by Moritz Kaposi, refers to a disseminated cutaneous infection with herpesvirus type 1 or 2, vaccinia virus, or coxsackievirus A16 in a patient with another underlying dermatosis. When herpesvirus type 1 or 2 is the pathogenic virus, the term "eczema herpeticum" is used, independent of the underlying dermatologic diagnosis that preceded the eruption. KVE is most often seen in patients with underlying atopic dermatitis, but has also been seen in association with other papulosquamous and acantholytic disorders.
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