Long-term improvement of insulin sensitivity during CPAP therapy in the obstructive sleep apnoea syndrome.

Background: We recently demonstrated that continuous positive airway pressure (CPAP) therapy rapidly improves insulin sensitivity within 2 days in non-diabetic patients with obstructive sleep apnea syndrome. In these very patients we investigated whether this improvement of insulin sensitivity is maintained during long-term CPAP therapy.

Material/methods: After a mean of 2.