Development and validation of a comprehensive new hepatobiliary software. Part II: Segmental liver function.

Objective: This study was undertaken to develop comprehensive new hepatobiliary software to quantify segmental and lobar liver function and to obtain FDA approval.

Methods: Hepatobiliary software written on JAVA platform and loaded on to a PC accepts 99mTc-HIDA dicom image data transferred from a gamma camera. Liver boundary was determined by threshold-based auto edge detection and liver height at right midclavicular (RMCL) line.

Segmentation of the gallbladder: effect on bile entry and exit and its clinical relevance in a patient with abdominal pain.

Background: The effects of folds or septa on gallbladder filling and emptying are not known.

Methods: Gallbladder filling and emptying were measured in seven patients with two chambers (segmental) and compared with 10 subjects with a single chamber (control). Percent bile flow into gallbladder, and percent ejection fraction from the proximal and distal segments, and entire gallbladder were measured with cholecystokinin.