Publications by authors named "Thomas Merciecca"
Type VI secretion systems (T6SS), recently described in hypervirulent K. pneumoniae (hvKp) strains, are involved in bacterial warfare but their role in classical clinical strains (cKp) has been little investigated. In silico analysis indicated the presence of T6SS clusters (from zero to four), irrespective of the strains origin or virulence, with a high prevalence in the K.
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- The text discusses a Gram-negative pathogen known for causing both community and hospital-acquired infections, highlighting its classification into multidrug-resistant and hypervirulent strains based on their genetic makeup.
- It aims to provide an overview of mouse models used to study various infectious processes, such as gastrointestinal colonization and urinary or pulmonary infections.
- The research focuses on the bacterial functions aiding in colonization and infection spread, which is essential for developing new treatments that can enhance immune responses or modify gut bacteria to reduce infections.