Indirect Costs of Alzheimer's Disease: Unpaid Caregiver Burden and Patient Productivity Loss.

Objectives: The direct medical costs associated with Alzheimer's disease (AD) in the United States have been estimated to be over $360 billion, but this value does not reflect the substantial financial burden on unpaid caregivers and society. We estimated the economic burden of unpaid caregivers and patient productivity loss due to AD across all disease severity stages to better understand the indirect impacts of AD.

Methods: We performed a narrative literature review to identify estimates of unpaid caregiver burden and market productivity loss.