Publications by authors named "Thomas M Large"

Purpose: To report the peri-implant fracture rates after locked plating of distal femur fractures and examine risk factors.

Methods: Over a 7 year period, 89 AO/OTA 33A/C distal femur fractures were identified and reviewed. After excluding treatment with intramedullary nails, age under 50, those with the proximal femur protected, or those without 6 months of follow-up, 42 distal femur fractures in 41 patients, mean age 72.

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Case: A 45-year-old man appeared to have a central (protrusio) hip dislocation but actually had a transverse posterior wall acetabulum fracture with irreducible posterior dislocation due to impalement of the femoral head on the ischial spine. He underwent urgent open reduction on presentation and subsequent internal fixation in a staged manner. He developed avascular necrosis at 18 months postoperatively.

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Introduction: Optimal treatment of high-risk ankle fractures in older, comorbid patients is unknown. Results of open reduction internal fixation (ORIF) versus tibiotalocalcaneal (TTC) fusion nailing for the treatment of high-risk geriatric ankle fractures were investigated.

Materials And Methods: Results of ORIF versus TTC fusion nailing were evaluated via retrospective case-control cohort study of 60 patients over age 50 with an open ankle fracture or one with at least 50% talar subluxation and at least 1 high-risk comorbidity: diabetes mellitus (DM), peripheral vascular disease, immunosuppression, active smoking, or a BMI > 35.

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Tibial plateau posterolateral fragments, especially those associated with articular depression, are difficult to capture and support with anteriorly or lateral based implants. Applying implants to the posterior plateau has traditionally involved a prone approach or fibular osteotomy, especially when access to both the medial and lateral sides is necessary, such as a bicondylar posterior coronal shear fracture pattern. By combining two previously described techniques for posterolateral rim plating and bicondylar hoop plating, we describe a novel technique to apply a posterior bicondylar hoop implant in the supine position without fibular osteotomy for bicondylar posterior coronal shear injuries.

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Article Synopsis
  • Despite the common use of antibiotics, surgical site infections remain prevalent in patients with fractures, prompting the need to explore better prevention methods.
  • An open-label randomized clinical trial tested the impact of intrawound vancomycin powder on reducing deep surgical site infections in high-risk patients undergoing tibial plateau or pilon fracture surgeries across multiple US trauma centers.
  • Results showed that the treatment group had a lower incidence of deep infections (6.4%) compared to the control group (9.8%), with the vancomycin specifically showing a significant effect on gram-positive infections, indicating its potential as an effective intervention in surgical settings.
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Article Synopsis
  • Posttraumatic avascular necrosis (AVN) is a condition that occurs after fractures in areas with limited blood supply, like the hip and shoulder, leading to bone death due to lack of blood flow.
  • The risk factors for developing AVN vary by location and fracture type, with femoral neck fractures posing a higher risk if displaced, while scaphoid fractures have a clear link to AVN when there's nonunion.
  • Treatment options include total hip arthroplasty for significant cases, and newer surgical techniques may help reduce AVN risk, though the debate continues on the best approach for scaphoid nonunions.
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Objectives: To determine whether interobserver technical variations and errors in the measurement of compartment pressures may affect measurement accuracy.

Methods: Four above-knee cadaveric specimens were used to create a consistent model of lower leg compartment syndrome. Thirty-eight physicians examined the limbs and measured 4 compartment pressures using the Intra-Compartmental Pressure Monitor (Stryker Orthopaedics).

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Background: We hypothesized that internal fixation procedures performed on trauma intensive care unit (ICU) patients with systemic infections, some also febrile, would be at increased risk for deep infection.

Methods: A total of 128 patients (mean age, 37.4 years; mean Injury Severity Score [ISS], 34.

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Limited data are available on the use of internal fixation in combat zone hospitals. The authors performed a retrospective review of 713 surgical cases during 2 Operation Enduring Freedom deployments to a Level III theater hospital in 2007 and 2009 to 2010. The epidemiology and short- to intermediate-term outcomes of patients treated with internal fixation devices were studied.

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Objectives: To determine whether negative pressure wound therapy (NPWT) affects antibiotic elution in simulated femur fractures treated with antibiotic impregnated polymethylmethacrylate (PMMA) beads and whether fascial closure between beads and sponge affects the outcome.

Methods: PMMA beads containing vancomycin and tobramycin were placed adjacent to bilateral corticotomies created in 20 anesthetized pigs. In 1 leg, NPWT was applied with the sponge either in direct contact with the beads or superficial to reapproximated fascia lata.

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Fifty periprosthetic supracondylar femur fractures above a total knee arthroplasty were reviewed. Fractures were closed Lewis and Rorabeck type II with a stable prosthesis. Twenty-nine patients (group I), were treated with locked condylar plating.

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Purpose: To biomechanically compare the Jobe transosseous ulnar collateral ligament (UCL) reconstruction procedure and an interference screw reconstruction (ISR) technique versus the intact elbow UCL.

Methods: Intact stiffness of 10 matched cadaveric elbow pairs was tested via submaximal valgus loading at 4 flexion angles. From each pair, a metal ISR and a traditional transosseous Jobe reconstruction was performed with the use of matched hamstring tendon grafts.

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