Anterior total hip arthroplasty using a metaphyseal bone-sparing stem: component alignment and early complications.

Background: Limited-incision total hip arthroplasty (THA) preserves hip abductors, posterior capsule, and external rotators potentially diminishing dislocation risk. However, potential complications also exist, such as component malposition. Specific implants have been manufactured that enhance compatibility with this technique, while preserving metaphyseal bone; however, little data exists documenting early complications and component position.

The protective role of the pericellular matrix in chondrocyte apoptosis.

Introduction: This study was designed to quantify the role of the pericellular matrix (PCM) in chondrocyte apoptosis using chondrons, which are a cartilage functional unit including a chondrocyte and its associated PCM.

Methods: Chondrocytes and chondrons were enzymatically isolated from human articular cartilage and exposed to monosodium iodoacetate (MIA) and staurosporine for apoptosis induction. Chondrons were defined by the presence of type VI collagen, a basic component of the PCM.

A model for studying human articular cartilage integration in vitro.

One of the major obstacles hindering cartilage repair is the integration of the reparative cartilage with the recipient cartilage. The purpose of this study was to develop an in vitro model that can be conveniently applied to simulate and improve the integration of tissue engineered cartilage with native articular cartilage. This model, a cartilage integration construct, consists of a cartilage explant and isolated chondrocytes.

Minimally invasive total hip arthroplasty: experience at Saint Louis University.

Minimally invasive total hip arthroplasty is used to describe both newer surgical approaches or simply smaller than standard incisions for the implantation of artificial hip joints. These new techniques have created interest, misunderstanding and controversy for patients and physicians. However, early indications are that minimally invasive hip surgery is an improvement compared to traditional surgery.