Enhanced Thromboresistance and Endothelialization of a Novel Fluoropolymer-Coated Left Atrial Appendage Closure Device.

Background: Device-related thrombus (DRT) after left atrial appendage closure (LAAC) procedures is a rare but potentially serious event. Thrombogenicity and delayed endothelialization play a role in the development of DRT. Fluorinated polymers are known to have thromboresistant properties that may favorably modulate the healing response to an LAAC device.

Cardiac computed tomography following Watchman FLX implantation: device-related thrombus or device healing?

Aims: Cardiac computed tomography (CT) is increasingly utilized during follow-up after left atrial appendage closure (LAAC). Hypoattenuated thickening (HAT) is a common finding and might represent either benign device healing or device-related thrombosis (DRT). The appearance and characteristics of HAT associated with the Watchman FLX have not been previously described.

Teleportation of entanglement over 143 km.

As a direct consequence of the no-cloning theorem, the deterministic amplification as in classical communication is impossible for unknown quantum states. This calls for more advanced techniques in a future global quantum network, e.g.

Cyclic (amino)(imino)carbene complexes by borylene transfer to isocyanides.

Here we report the facile formation of boron-containing cyclic (amino)(imino)carbene complexes by reaction of a chromium borylene complex [(OC)(5)Cr=B=N(SiMe(3))(2)] with isocyanides.

Quantum erasure with causally disconnected choice.

The counterintuitive features of quantum physics challenge many common-sense assumptions. In an interferometric quantum eraser experiment, one can actively choose whether or not to erase which-path information (a particle feature) of one quantum system and thus observe its wave feature via interference or not by performing a suitable measurement on a distant quantum system entangled with it. In all experiments performed to date, this choice took place either in the past or, in some delayed-choice arrangements, in the future of the interference.

Experimental quantum teleportation over a high-loss free-space channel.

We present a high-fidelity quantum teleportation experiment over a high-loss free-space channel between two laboratories. We teleported six states of three mutually unbiased bases and obtained an average state fidelity of 0.82(1), well beyond the classical limit of 2/3.

Quantum teleportation over 143 kilometres using active feed-forward.

The quantum internet is predicted to be the next-generation information processing platform, promising secure communication and an exponential speed-up in distributed computation. The distribution of single qubits over large distances via quantum teleportation is a key ingredient for realizing such a global platform. By using quantum teleportation, unknown quantum states can be transferred over arbitrary distances to a party whose location is unknown.

Calibrating the interaction matrix for the LINC-NIRVANA high layer wavefront sensor.

LINC-NIRVANA is a near-infrared Fizeau interferometric imager that will operate at the Large Binocular Telescope. In preparation for the commissioning of this instrument, we conducted experiments for calibrating the high-layer wavefront sensor of the layer-oriented multi-conjugate adaptive optics system. For calibrating the multi-pyramid wavefront sensor, four light sources were used to simulate guide stars.

First laboratory results with the LINC-NIRVANA high layer wavefront sensor.

In the field of adaptive optics, multi-conjugate adaptive optics (MCAO) can greatly increase the size of the corrected field of view (FoV) and also extend sky coverage. By applying layer oriented MCAO (LO-MCAO) [4], together with multiple guide stars (up to 20) and pyramid wavefront sensors [7], LINC-NIRVANA (L-N for short) [1] will provide two AO-corrected beams to a Fizeau interferometer to achieve 10 milliarcsecond angular resolution on the Large Binocular Telescope. This paper presents first laboratory results of the AO performance achieved with the high layer wavefront sensor (HWS).

Violation of local realism with freedom of choice.

Bell's theorem shows that local realistic theories place strong restrictions on observable correlations between different systems, giving rise to Bell's inequality which can be violated in experiments using entangled quantum states. Bell's theorem is based on the assumptions of realism, locality, and the freedom to choose between measurement settings. In experimental tests, "loopholes" arise which allow observed violations to still be explained by local realistic theories.

Chemoselective boron-carbon bond cleavage by hydroboration of borirenes.

We report on the hydroboration of 1-[bis(trimethylsilyl)amino]-2,3-diethylborirene (3) with 9-borabicyclo[3.3.1]nonane (9-BBN), which led through ring-opening to an amino(vinyl)borane.

Histopathologic description of Wingspan stent in acute ischemic stroke.

Objective And Importance: We report the histopathologic examination of Wingspan stent in acute ischemic stroke.

Clinical Presentation: A 75-year-old female presented with acute left-hemiplegia due to right carotid terminus occlusion. Mechanical embolectomy was unsuccessful.

Comparison of inflammatory response after implantation of sirolimus- and paclitaxel-eluting stents in porcine coronary arteries.

Background: Although both sirolimus (CYPHER) and paclitaxel (TAXUS) drug-eluting stents have demonstrated efficacy and safety in clinical trials, human autopsy data have raised concerns about long-term healing and the potential for local inflammatory reactions.

Methods And Results: Overlapping stents (CYPHER drug-eluting stents, Bx SONIC bare metal stents, TAXUS drug-eluting stents, and Liberté bare metal stents) were implanted in noninjured coronary arteries of 58 domestic swine. Histopathological evaluation of proximal, overlapped, and distal stented segments was determined with emphasis on inflammation at 30, 90, and 180 days.

Borylene-based direct functionalization of organic substrates: synthesis, characterization, and photophysical properties of novel pi-conjugated borirenes.

Room temperature photolysis of aminoborylene complexes, [(CO)(5)M=B=N(SiMe(3))(2)] (1: M = Cr, 2: Mo) in the presence of a series of alkynes and diynes, 1,2-bis(4-methoxyphenyl)ethyne, 1,2-bis(4-(trifluoromethyl)phenyl)ethyne, 1,4-diphenylbuta-1,3-diyne, 1,4-bis(4-methoxyphenyl)buta-1,3-diyne, 1,4-bis(trimethylsilylethynyl)benzene and 2,5-bis(4-N,N-dimethylaminophenylethynyl)thiophene led to the isolation of novel mono and bis-bis-(trimethylsilyl)aminoborirenes in high yields, that is [(RC=CR)(mu-BN(SiMe(3))(2)], (3: R = C(6)H(4)-4-OMe and 4: R = C(6)H(4)-4-CF(3)); [{(mu-BN(SiMe(3))(2)(RC=C-)}(2)], (5: R = C(6)H(5) and 6: R = C(6)H(4)-4-OMe); [1,4-bis-{(mu-BN(SiMe(3))(2)(SiMe(3)C=C)}benzene], 7 and [2,5-bis-{(mu-BN(SiMe(3))(2) ((C(6)H(4)NMe(2))C=C)}-thiophene], 8. All borirenes were isolated as light yellow, air and moisture sensitive solids. The new borirenes have been characterized in solution by (1)H, (11)B, (13)C NMR spectroscopy and elemental analysis and the structural types were unequivocally established by crystallographic analysis of compounds 6 and 7.

Group VI metal aminoborylene complex-catalyzed demercuration reactions of bis(alkynyl)mercurials.

The first catalytic application of the Group VI metal borylene complexes [(CO)(5)M[double bond]BN(SiMe(3))(2)] involves the demercuration reaction of bis(alkynyl)mercurials, [Hg(C[triple bond]CR)(2)], with formation of a series of buta-1,3-diynes.

A wavelength-tunable fiber-coupled source of narrowband entangled photons.

We demonstrate a wavelength-tunable, fiber-coupled source of polarization- entangled photons with extremely high spectral brightness and quality of entanglement. Using a 25 mm PPKTP crystal inside a polarization Sagnac interferometer we detect a spectral brightness of 273000 pairs (s mW nm)(-1), a factor of 28 better than comparable previous sources while state tomography showed the two-photon state to have a tangle of T = 0.987.