Publications by authors named "Thomas Haslam"
Estimating the real world daily usage and cost for exenatide twice daily and liraglutide in Germany, the Netherlands, and the UK based on volumes dispensed by pharmacies.
Clinicoecon Outcomes Res
February 2015
Article Synopsis
- GLP-1 receptor agonists, like exenatide and liraglutide, are used to help adults with type 2 diabetes manage their blood sugar levels, and their cost is an important factor for treatment choices.
- This study analyzed prescription data from Germany, the Netherlands, and the UK to calculate the average daily doses and costs of these medications in real-world use.
- Findings showed that while both medications had average daily dosages aligning with recommended levels, exenatide was generally less expensive than liraglutide across these countries, providing insights for healthcare decision-makers.
Objectives: The aim of this study was to assess acute ablation injuries seen on late gadolinium enhancement (LGE) magnetic resonance imaging (MRI) immediately post-ablation (IPA) and the association with permanent scar 3 months post-ablation (3moPA).
Background: Success rates for atrial fibrillation catheter ablation vary significantly, in part because of limited information about the location, extent, and permanence of ablation injury at the time of procedure. Although the amount of scar on LGE MRI months after ablation correlates with procedure outcomes, early imaging predictors of scar remain elusive.
Background: Atrial fibrosis is a hallmark of atrial structural remodeling (SRM) and leads to structural and functional impairment of left atrial (LA) and persistence of atrial fibrillation (AF). This study was conducted to assess LA reverse remodeling after catheter ablation of AF in mild and moderate-severe LA SRM.
Methods: Catheter ablation was performed in 68 patients (age 62 ± 14 years, 68% males) with paroxysmal (n = 26) and persistent (n = 42) AF.
Unlabelled: MRI for AF Patient Selection and Ablation Approach.
Introduction: Left atrial (LA) fibrosis and ablation related scarring are major predictors of success in rhythm control of atrial fibrillation (AF). We used delayed enhancement MRI (DE-MRI) to stratify AF patients based on pre-ablation fibrosis and also to evaluate ablation-induced scarring in order to identify predictors of a successful ablation.
Background: Lone atrial fibrillation (AF) is thought to be a benign type or an early stage of the disease.
Objective: This study sought to compare the left atrium (LA) substrate using delayed-enhanced magnetic resonance imaging (DE-MRI) in patients with lone AF versus those with comorbidities.
Methods: Forty of 333 included patients met criteria for lone AF.
Background: We evaluated scar lesions after initial and repeat catheter ablation of atrial fibrillation (AF) and correlated these regions to low-voltage tissue on repeat electroanatomic mapping. We also identified gaps in lesion sets that could be targeted and closed during repeat procedures.
Methods And Results: One hundred forty-four patients underwent AF ablation and received a delayed-enhancement MRI at 3 months after ablation.