Lessons Learned from the Development and Roll-Out of the rVSVΔG-ZEBOV-GP Vaccine to Inform Marburg Virus and Vaccines.

This review describes key aspects of the development of the rVSVΔG-ZEBOV-GP Ebola vaccine and key activities which are continuing to further expand our knowledge of the product. Extensive partnerships and innovative approaches were used to address the various challenges encountered during this process. The rVSVΔG-ZEBOV-GP Ebola vaccine was initially approved by the European Medicines Agency and prequalified by the World Health Organization in November 2019.

Pure laparoscopic liver resection for large malignant tumors: does size matter?

Background: Laparoscopic liver resection (LLR) for large malignant tumors can be technically challenging. Data on this topic are scarce, and many question its feasibility, safety, and oncologic efficiency. This study aimed to assess outcomes of LLR for large (≥ 5 cm) and giant (≥ 10 cm) malignant liver tumors.

Postoperative chyle leak after major pancreatic resections in patients who receive enteral feed: risk factors and management options.

Background: Chyle leak complicates 1.3-10.8 % of pancreatic resections.

Implementation of enhanced recovery programme after pancreatoduodenectomy: a single-centre UK pilot study.

Introduction: Data on enhanced recovery programmes after pancreatoduodenectomy (ERP-PD) is limited. The aim of this pilot study was to evaluate the feasibility, safety and clinical outcomes of ERP-PD when implemented at a high-volume UK university referral centre.

Methods: This was an observational single-surgeon case-control study (before-and-after pathway).