Publications by authors named "Thomas Gutschi"

Objective: To evaluate whether biopsy cores taken via a transrectal approach from the anterior apical region of the prostate in a repeat-biopsy population can result in an increased overall cancer detection rate and in more accurate assessment of the Gleason score.

Patients And Methods: The study was a prospective, randomised (end-fire vs side-fire ultrasound probe) evaluation of 288 men by repeat transrectal saturation biopsy with 28 cores taken from the transition zone, base, mid-lobar, anterior and the anterior apical region located ventro-laterally to the urethra of the peripheral zone.

Results: The overall prostate cancer detection rate was 44.

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Aims: To investigate the potential prognostic impact of the lymphocyte-monocyte ratio (LMR) in a large European cohort of patients with localised upper urinary tract urothelial carcinoma (UTUC). The LMR as an indicator of systemic inflammatory response has been shown to represent a potential prognostic factor in various types of human cancers. Up to date, the prognostic significance of the LMR in UTUC has not been evaluated.

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Article Synopsis
  • New imaging techniques have been developed to enhance the diagnosis and staging of early-stage prostate cancer (PCa), including traditional transrectal ultrasound and newer methods like real-time elastography and multiparametric MRI.
  • While conventional ultrasound aids in guiding biopsies, contrast-enhanced ultrasound shows mixed results in detecting cancer, and computer-based analysis of ultrasound signals has proven effective for patients with prior biopsies.
  • Despite some promising findings, there is currently no consensus on the routine use of these advanced imaging techniques, highlighting the need for more extensive prospective studies.
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