Publications by authors named "Thomas Gorniak"

A ptychographical coherent diffractive imaging experiment in the water window with focused soft X-rays at 500 eV is reported. An X-ray beam with high degree of coherence was selected for ptychography at the P04 beamline of PETRA III synchrotron radiation source. The beam coherence was measured with the newly developed non-redundant array method, and a coherence length of 4.

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Melanin within melanosomes exists as eumelanin or pheomelanin. Distributions of these melanins have been studied extensively within tissues, but less often within individual melanosomes. Here, we apply X-ray fluorescence analysis with synchrotron radiation to survey the nanoscale distribution of metals within purified melanosomes of mice.

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Melanosomes are highly specialized organelles that produce and store the pigment melanin, thereby fulfilling essential functions within their host organism. Besides having obvious cosmetic consequences--determining the color of skin, hair and the iris--they contribute to photochemical protection from ultraviolet radiation, as well as to vision (by defining how much light enters the eye). Though melanosomes can be beneficial for health, abnormalities in their structure can lead to adverse effects.

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Article Synopsis
  • X-ray ptychography is an advanced imaging technique that merges the benefits of coherent diffractive imaging with the ability to image larger objects.
  • A significant challenge in this method is the mechanical drift during data collection, which can negatively impact image quality and resolution.
  • The study presents a method to systematically correct for positional drift, resulting in improved reconstructions of degraded images, like those of a Siemens star dataset.
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Article Synopsis
  • X-ray microscopy has advantages like deep penetration and chemical analysis through near-edge resonances.
  • The study utilizes ptychography, a technique that doesn't need isolated samples, to achieve resonant imaging and distinguish between two oxygen-rich materials.
  • The research includes imaging freeze-dried Deinococcus radiodurans cells to demonstrate potential applications for chemical mapping in unsliced biological samples.
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