Pulse pressure variations adjusted by alveolar driving pressure to assess fluid responsiveness.

Objective: To evaluate the ability of DeltaPP/DeltaP [pulse pressure variations (DeltaPP) adjusted by alveolar pressure variations (DeltaP = Pplat-PEEPtot)] in predicting fluid responsiveness, to compare its accuracy to that of DeltaPP used alone and to evaluate the influence of tidal volume (Vt) on these two indices.

Design: Prospective study.

Setting: A 22-bed general intensive care unit (ICU).