Publications by authors named "Thomas G Wichman"
Article Synopsis
- - The study re-analyzed genetic data from COVID-19 patients and found that genes related to eicosanoid synthesis were more active in patients with severe cases, particularly in goblet cells of the nasopharynx.
- - Researchers compared lipid metabolites in infected vs. uninfected individuals and discovered higher levels of certain lipids like Arachidonic Acid (AA) and Eicosapentaenoic Acid (EPA) in COVID-19 patients, which correlated with the severity of the disease.
- - The findings suggest a link between eicosanoid gene expression in the nasopharynx, increased serum inflammatory lipids, and the activation of DNA damage pathways in white blood cells, indicating a potential mechanism influencing the severity of COVID
