Publications by authors named "Thomas F Callaghan"
Three commercially available integrated rapid DNA instruments were tested as a part of a rapid DNA maturity assessment in July of 2018. The assessment was conducted with sets of blinded single-source reference samples provided to participants for testing on the individual rapid platforms within their laboratories. The data were returned to the National Institute of Standards and Technology (NIST) for review and analysis.
View Article and Find Full Text PDFRapid DNA platforms are fully integrated systems capable of producing and analyzing short tandem repeat (STR) profiles from reference sample buccal swabs in less than two hours. The technology requires minimal user interaction and experience making it possible for high quality profiles to be generated outside an accredited laboratory. The automated production of point of collection reference STR profiles could eliminate the time delay for shipment and analysis of arrestee samples at centralized laboratories.
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- * DNA analysts must document their assumptions and interpretations, and qualified examiners should be able to review these reports to understand the reasoning behind the findings.
- * The interpretation process involves various technical considerations that require internal validation studies, and the guidelines should also address potential biases in conclusions drawn from reference samples.