Patient-Specific Instrumentation vs Standard Referencing in Total Ankle Arthroplasty: A Comparison of the Radiologic Outcome.

Background: Existing literature on the superiority of patient-specific instrumentation (PSI) in total ankle arthroplasty (TAA) over standard referencing (SR) is limited. Advantages presented include better implant alignment, shorter operating times, and increased accuracy of implant size prediction. The aim of this retrospective study was to analyze PSI in the hands of an experienced foot and ankle surgeon new to both PSI and SR for this specific implant, in regard to determining implant alignment, operative times, and radiologic short-term outcome and predicting implant size for tibial and talar components.

Knee-to-Ankle Mosaicplasty for the Treatment of Osteochondral Lesions of the Ankle Joint.

Background: Osteochondral lesions are frequently seen in athletes after ankle injuries. At this time, osteochondral autologous transplantation (OATS, mosaicplasty) is the only surgical treatment that replaces the entire osteochondral unit in symptomatic lesions.

Purpose: To evaluate the clinical and radiological midterm to long-term outcome of ankles treated with knee-to-ankle mosaicplasty.

Knee-to-ankle mosaicplasty for the treatment of osteochondral lesions of the ankle joint.

Background: Osteochondral lesions are frequently seen in athletes after ankle injuries. At this time, osteochondral autologous transplantation (OATS, mosaicplasty) is the only surgical treatment that replaces the entire osteochondral unit in symptomatic lesions.

Purpose: To evaluate the clinical and radiological midterm to long-term outcome of ankles treated with knee-to-ankle mosaicplasty.

Radiographic evaluation of frontal talar edge configuration for osteochondral plug transplantation.

For successful reconstruction of osteochondral lesions of the talus, the anatomic configuration of the talar edge must be respected. This study evaluated the radiographic configuration of the talar edge in the anterior-posterior (AP) view by analyzing medial and lateral talar edge angles and radii in 81 patients with a true AP view and without ankle pathology. The mean lateral talar edge angle was 91.

TNM staging with FDG-PET/CT in patients with primary head and neck cancer.

Purpose: PET/CT, PET+CT, and CT were compared concerning accuracies in TNM staging and malignancy detection in head and neck cancer. The impact of PET/CT compared to the other imaging modalities on therapy management was assessed.

Materials And Methods: Fifty-five patients with suspected head and neck primary cancer underwent whole-body FDG-PET/CT.

[Preventive whole-body screening encompassing modern imaging using magnetic resonance tomography].

Background: With respect to the prognosis of the population and costs, the focus of the health-care system should lie more on preventive medicine in the future. The value of screening examinations as secondary prevention is, however, controversial, as only few investigations exist.

Patients And Methods: The authors report on 1,007 consecutive patients who underwent a screening examination based on clinical examinations and whole-body magnetic resonance imaging (MRI) of the brain, arterial system, heart and abdomen in a private outpatient center.

Retroperitoneal displacement of ovary and fallopian tube: a complication of surgical management of incarcerated inguinal hernia in female infants.

Sliding indirect inguinal hernias containing the ipsilateral uterine adnexa are not uncommon in female infants. We report a case of a 12-year-old girl presenting with a benign tumor (serous cystadenofibroma) in a retroperitoneally located ovary. The patient had a history of hernia repair in the neonatal period.

Dual modality of 18F-fluorodeoxyglucose-positron emission tomography/computed tomography in patients with cervical carcinoma of unknown primary.

Objective: To evaluate an optimized F-18-flurodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) acquisition protocol for head and neck cancer and assess the usefulness of combined FDG-PET/CT in locating unknown primary tumors in patients with biopsy-proven cervical lymph node metastases.

Subjects And Methods: Twenty-one patients with cervical lymph node metastases of unknown primary tumors underwent staging with FDG-PET/CT. The images of FDG-PET alone, CT alone, FDG-PET/CT read side by side and fused and FDG-PET/CT were evaluated separately by 2 physicians.

Unknown primary tumors: detection with dual-modality PET/CT--initial experience.

Purpose: To retrospectively evaluate fused positron emission tomography (PET)/computed tomography (CT) in depicting the primary lesion in cancer of an unknown primary tumor, compared with PET, CT, and PET and CT side-by-side evaluation.

Materials And Methods: Institutional review board approval and informed consent were obtained. Forty-five patients (26 men and 19 women) with metastatic cervical adenopathy (n = 18) or extracervical metastases (n = 27) of unknown primary tumor were included.

Albumin targeting of damaged muscle fibres in the mdx mouse can be monitored by MRI.

Increased sarcolemmal permeability has been implicated as a major pathological event in muscular dystrophies. In our study, we evaluated whether damaged muscle fibres can be specifically targeted using albumin as a carrier. We tagged human serum albumin (HSA) with Gadolinium (Gd) and systemically applied this compound (Gd-DTPA-HSA) to wildtype and dystrophin-deficient mdx mice.

Double-stent method: therapeutic alternative for small wide-necked aneurysms. Technical note.

The authors present two cases of patients with small, acutely ruptured, wide-necked aneurysms of the distal vertebral artery that were not amenable to conventional coil embolization and were instead treated by means of a double-stent method in which one stent was placed inside another. Angiography performed immediately after the procedure revealed a significant reduction in aneurysm filling; total occlusion of the lesion was observed after 7 days and confirmed 6 months later in both aneurysms. By placing one stent inside the other, stent permeability can be reduced, which may result in significant hemodynamic changes with accelerated aneurysm thrombosis.

Acquisition protocol considerations for combined PET/CT imaging.

Unlabelled: Since its introduction in 1998, dual-modality PET/CT imaging has received great attention in the medical community. For the first time, patients can be examined with both CT and PET in a single examination. A whole-body survey is the standard mode of acquisition.

Symptomatic migraine and sensitization of trigeminal nociception associated with contralateral pontine cavernoma.

A 38-year-old woman is described with symptomatic strictly right-sided migraine associated with a pontine cavernoma affecting the contralateral (left) nucleus raphe magnus. A persistent facilitation of the right-sided trigeminal nociception was detected interictally using the 'nociception specific' blink reflex, which was more pronounced during the acute attack. This case shows for the first time, an impairment of the anti-nociceptive brainstem nuclei and the facilitation of the trigeminal nociception in the same subject, thus providing further evidence for the key role of the brainstem raphe nuclei in the pathophysiology of migraine.

Focal tracer uptake: a potential artifact in contrast-enhanced dual-modality PET/CT scans.

Unlabelled: This study was performed to evaluate a possible artifact related to the administration of intravascular contrast agent in dual-modality PET/CT imaging.

Methods: Thirty oncology patients underwent whole-body PET/CT. CT images, which were collected in the presence of intravenous and oral iodinated contrast agent, were used for PET attenuation correction.

Endovascular treatment of unruptured intracranial aneurysms.

Background And Purpose: Intracranial aneurysms are common, with an overall frequency ranging from 0.8% to 10%. Because prognosis after subarachnoid hemorrhage is still very poor, treatment of unruptured aneurysms, either neurosurgically or endovascularly, has been advocated.