Predictors of heart failure in patients with stable coronary artery disease: a PEACE study.

Background: Heart failure (HF) is a disease commonly associated with coronary artery disease. Most risk models for HF development have focused on patients with acute myocardial infarction. The Prevention of Events with Angiotensin-Converting Enzyme Inhibition population enabled the development of a risk model to predict HF in patients with stable coronary artery disease and preserved ejection fraction.

QT dispersion and heart rate predict the risk of sudden unexpected cardiac death in men: the Manitoba Follow-Up Study.

As many as half of all sudden cardiac deaths are unexpected, with no preceding symptoms or signs of cardiac problems. Since 1948, the Manitoba Follow-up Study has prospectively recorded routine medical information and resting electrocardiographic (ECG) findings from a cohort of 3983 men. During 58 years of follow-up, 180 men experienced sudden unexpected cardiac death (SUCD).

Sudden cardiac death in patients with stable coronary artery disease and preserved left ventricular systolic function.

Although sudden cardiac death (SCD) has been extensively studied in patients with coronary artery disease (CAD) and low ejection fraction, prediction of SCD among individuals with preserved left ventricular systolic function is less well understood. We randomized 8,290 patients with stable CAD with preserved left ventricular systolic function to trandolapril or placebo in a secondary coronary prevention trial, and we used Cox proportional hazards models to identify independent baseline predictors of SCD during 4.8 year follow-up (median).