Publications by authors named "Thomas Doering"

Article Synopsis
  • The study looked at how people's bodies respond during three different exercise tests for those who have unexplained breathlessness.
  • These tests were the treadmill cardiopulmonary exercise test (CPX), the 6-minute walk test (6MWT), and the timed up and go test (TUGT).
  • The results showed that the CPX caused the biggest changes in heart rate and breathing, while the 6MWT and TUGT showed smaller responses, but the TUGT still increased physical responses even though it was shorter.
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Objectives: The adolescent development period is critical for rugby league athletes, given the physical growth, neuromuscular adaptation, and skill acquisition that occurs. Secondary schools play an important role in the development of adolescent rugby league players; however, players may be selected into rugby league academies and development programs outside of school, as well as participating in additional sports. In turn, the training loads these young athletes accrue and the implications of these loads are currently unknown.

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Purpose: Rigorous evidence concerning the reliability of physical tests among young athletes is lacking. Therefore, this study aimed to comprehensively determine the retest reliability of the most commonly used tests to assess physical qualities in adolescent rugby league players, and to provide the standard error of measurement and minimal detectable change for each test to support objective athlete monitoring.

Method: A repeated-measures design was employed with 50 adolescent, schoolboy rugby league players (16.

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This study compared heart rate variability (HRV) parameters of cardiovascular autonomic regulation between well-trained masters and young cyclists at rest, during and following a continuous cycle (CTS) protocol. Ten masters (age = 56 ± 5 years) and eight young (age = 26 ± 3 years) cyclists completed a 100 min experimental protocol consisting of a 60 min CTS cycling bout at 95% of Ventilatory Threshold 2 followed by 40 min of supine recovery. Beat-to-beat heart rate was measured continuously, and HRV parameters analysed at standardised 5 min intervals during rest, exercise and recovery.

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The relationship between heart rate variability (HRV) and training load in team-sport is unknown. We therefore assessed relations between completed training-load in the previous 1-, 3- and 7-days and waking HRV in professional Australian Rules Football. Linear-mixed models analysed changes in HRV, considering training load from the previous 1-, 3- and 7-days.

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This study investigated the effect of high-intensity interval exercise on total and individual amino acid concentrations in red blood cells (RBCs) and plasma. Seven males (31 ± 13 yr) provided venous blood samples at rest, immediately and 15 min and 30 min following an 8-min high-intensity exercise bout. The exercise bout was 16 × 15 s cycle efforts at 0.

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Background: Understanding the physical qualities of male, adolescent rugby league players across age groups is essential for practitioners to manage long-term player development. However, there are many testing options available to assess these qualities, and differences in tests and testing protocols can profoundly influence the data obtained.

Objectives: The aims of this systematic review were to: (1) identify the most frequently used tests to assess key physical qualities in male, adolescent rugby league players (12-19 years of age); (2) examine the testing protocols adopted in studies using these tests; and (3) synthesise the available data from studies using the most frequently used tests according to age group.

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Trial matches are frequently used for team preparation in rugby league competitions, making it essential to understand the demands experienced to assess their specificity to actual competition. Consequently, this study aimed to compare the activity demands between pre-season trial matches and early in-season rugby league matches. Following a repeated-measures observational design, 39 semi-professional, male rugby league players from two clubs were monitored using microsensors during two trial matches and the first two in-season matches across two consecutive seasons.

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Exercise training prevents age-related decline in muscle function. Targeting epigenetic aging is a promising actionable mechanism and late-life exercise mitigates epigenetic aging in rodent muscle. Whether exercise training can decelerate, or reverse epigenetic aging in humans is unknown.

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We aimed to determine whether there was a relationship between pre-immobilization skeletal muscle size and the magnitude of muscle atrophy following 14 days of unilateral lower limb immobilization. Our findings ( = 30) show that pre-immobilization leg fat-free mass and quadriceps cross-sectional area (CSA) were unrelated to the magnitude of muscle atrophy. However, sex-based differences may be present, but confirmatory work is required.

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Skeletal muscle unloading due to joint immobilization induces muscle atrophy, which has primarily been attributed to reductions in protein synthesis in humans. However, no study has evaluated the skeletal muscle proteome response to limb immobilization using SWATH proteomic methods. This study characterized the shifts in individual muscle protein abundance and corresponding gene sets after 3 and 14 d of unilateral lower limb immobilization in otherwise healthy young men.

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This study investigates differences in physical activity between weekdays and weekend days, and its associations with sociodemographic and anthropometric characteristics in the U.S population using the NHANES 2011-2014 data. Physical activity was measured using ActiGraph GT3X+.

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Introduction: To improve maternal health outcomes, increased diversity is needed among pregnant people in research studies and community surveillance. To expand the pool, we sought to develop a network encompassing academic and community obstetrics clinics. Typical challenges in developing a network include site identification, contracting, onboarding sites, staff engagement, participant recruitment, funding, and institutional review board approvals.

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Skeletal muscle atrophy is a physiological response to disuse, aging, and disease. We compared changes in muscle mass and the transcriptome profile after short-term immobilization in a divergent model of high and low responders to endurance training to identify biological processes associated with the early atrophy response. Female rats selectively bred for high response to endurance training (HRT) and low response to endurance training (LRT; n = 6/group; generation 19) underwent 3 day hindlimb cast immobilization to compare atrophy of plantaris and soleus muscles with line-matched controls (n = 6/group).

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Background: Knowledge of age-related DNA methylation changes in skeletal muscle is limited, yet this tissue is severely affected by ageing in humans.

Methods: We conducted a large-scale epigenome-wide association study meta-analysis of age in human skeletal muscle from 10 studies (total n = 908 muscle methylomes from men and women aged 18-89 years old). We explored the genomic context of age-related DNA methylation changes in chromatin states, CpG islands, and transcription factor binding sites and performed gene set enrichment analysis.

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New Findings: What is the central question of this study? The extent to which genetics determines adaptation to endurance versus resistance exercise is unclear. Previously, a divergent selective breeding rat model showed that genetic factors play a major role in the response to aerobic training. Here, we asked: do genetic factors that underpin poor adaptation to endurance training affect adaptation to functional overload? What is the main finding and its importance? Our data show that heritable factors in low responders to endurance training generated differential gene expression that was associated with impaired skeletal muscle hypertrophy.

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This study aimed to determine if eight sessions of supramaximal but steady-state, set duration interval training in hypoxia enhanced measured anaerobic capacity and work performed during high intensity exercise. 21:370-377, 2020. Eighteen cyclists (O: 57 ± 7 ml·kg·min) were pair-matched for anaerobic capacity determined by maximal accumulated oxygen deficit (MAOD) and allocated to a 4-week interval training in hypoxia (IHT; FiO = 14.

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O'Connor, FK, Doering, TM, Minett, GM, Reaburn, PR, Bartlett, JD and Coffey, VG. Effect of divergent solar radiation exposure with outdoor versus indoor training in the heat: implications for performance. J Strength Cond Res 36(6): 1622-1628, 2022-The aim of this study was to determine physiological and perceptual responses and performance outcomes when completing high-intensity exercise in outdoor and indoor hot environments with contrasting solar radiation exposure.

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Context: Exercise in hot environments increases body temperature and thermoregulatory strain. However, little is known regarding the magnitude of effect that ambient temperature (Ta), relative humidity (RH), and solar radiation individually have on team-sport athletes.

Purpose: To determine the effect of these individual heat-stress variables on team-sport training performance and recovery.

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Background: Ageing is associated with DNA methylation changes in all human tissues, and epigenetic markers can estimate chronological age based on DNA methylation patterns across tissues. However, the construction of the original pan-tissue epigenetic clock did not include skeletal muscle samples and hence exhibited a strong deviation between DNA methylation and chronological age in this tissue.

Methods: To address this, we developed a more accurate, muscle-specific epigenetic clock based on the genome-wide DNA methylation data of 682 skeletal muscle samples from 12 independent datasets (18-89 years old, 22% women, 99% Caucasian), all generated with Illumina HumanMethylation (HM) arrays (HM27, HM450, or HMEPIC).

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Purpose: Due to age-related changes in the psychobiological state of masters athletes, this brief report aimed to compare training load responses using heart rate (HR) and ratings of perceived exertion (RPE) during standardized training sessions between masters and young cyclists.

Methods: Masters (n = 10; 55.6 [5.

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Objectives: To determine if a 4 d period of high carbohydrate intake can supercompensate muscle glycogen and exercise work capacity on back-to-back occasions.

Design: Seven trained cyclists (6 male, VOpeak: 57 ± 4 mL kg min) completed a 9-d experimental period, consisting of three intermittent exhaustive cycling trials on days 1 (trial 1), 5 (trial 2) and 9 (trial 3). Following trial 1 cyclists were fed a high carbohydrate diet (˜10 g kg day) for eight days to assess their capacity to repeatedly supercompensate muscle glycogen with 4 d recovery.

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Objective: To determine the effects of multi-ingredient protein (MIP) supplements on resistance exercise training (RT)-induced gains in muscle mass and strength compared with protein-only (PRO) or placebo supplementation.

Data Sources: Systematic search of MEDLINE, Embase, CINAHL and SPORTDiscus.

Eligibility Criteria: Randomised controlled trials with interventions including RT ≥6 weeks in duration and a MIP supplement.

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Background: The purpose of this study was to compare physical performance, perceptual and haematological markers of recovery in well-trained masters and young cyclists across 48 h following a bout of repeated high-intensity interval exercise.

Methods: Nine masters (mean ± SD; age = 55.6 ± 5.

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Background: Disparities in health perspectives between Indigenous and non-Indigenous populations are major concerns in many of the world's well-developed nations. Indigenous populations are largely less healthy, more prone to chronic diseases, and have an earlier overall mortality than non-Indigenous populations. Low levels of physical activity (PA) contribute to the high levels of disease in Indigenous Australians.

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