Publications by authors named "Thomas Cortier"

Understanding how interpersonal interactions and immunological factors shape SARS-CoV-2 transmission in households is crucial for designing control measures. We developed a Bayesian data augmentation transmission model to evaluate the effects of isolation, parental care, and vaccine-induced immunity on Delta variant transmission from the follow-up of 1,093 Israeli households (July-August 2021). Among the 2883 household contacts, 1096 (38%) were infected.

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Article Synopsis
  • Research on immune responses to neuraminidase (NA) is vital for improving influenza vaccines, particularly regarding its effect on infection susceptibility and infectivity.
  • A study in Managua, Nicaragua found that higher levels of antibodies against NA and hemagglutinin (HA) are linked to lower chances of influenza A/H3N2 infection, with distinct benefits from anti-NA antibodies in reducing infectivity.
  • These findings indicate that influenza vaccines targeting both NA and HA could enhance protection against infection and decrease the likelihood of spreading the virus among vaccinated individuals.
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Background: The incubation period of SARS-CoV-2 has been estimated for the known variants of concern. However, differences in study designs and settings make comparing variants difficult. We aimed to estimate the incubation period for each variant of concern compared with the historical strain within a unique and large study to identify individual factors and circumstances associated with its duration.

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Understanding how neurons cooperate to integrate sensory inputs and guide behavior is a fundamental problem in neuroscience. A large body of methods have been developed to study neuronal firing at the single cell and population levels, generally seeking interpretability as well as predictivity. However, these methods are usually confronted with the lack of ground-truth necessary to validate the approach.

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