Publications by authors named "Thomas Cc Yau"
Article Synopsis
- A study looked at how well patients with breast cancer that had spread to the liver do after surgery called hepatectomy, which removes part of the liver.
- Out of 2522 liver cancer patients between 1995 and 2014, only 21 had surgery for breast cancer, and their survival rates were compared to patients with colorectal cancer who also had surgery.
- The results showed that the breast cancer patients had similar short-term surgery outcomes and good survival rates, with 100% surviving the first year post-surgery, making hepatectomy a good treatment option for these patients.
Transarterial chemoembolization (TACE) is commonly used for the treatment of locally advanced hepatocellular carcinoma (HCC) by its dual effects of chemotherapy and ischemic hypoxia. However, one of the side effects of TACE is the introduction of hypoxic condition, which in turn activates hypoxia-induced survival pathways and enhances VEGF-induced neovascularization by stabilizing HIF-1α expression. Herein, the preclinical therapeutic efficacy of the combined treatment of everolimus, a novel mTOR inhibitor and TACE for the treatment of HCC was investigated.
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