spp. are frequently enriched in the gut microbiota of preterm neonates, and overgrowth is associated with necrotizing enterocolitis (NEC), nosocomial infections and late-onset sepsis. Little is known about the genomic and phenotypic characteristics of preterm-associated , as previous studies have focused on the recovery of antimicrobial-resistant isolates or culture-independent molecular analyses.
View Article and Find Full Text PDFspp. are commensals of the human microbiota, and a leading cause of opportunistic nosocomial infections. The incidence of multidrug resistant (MDR) strains of causing serious infections is increasing, and is an emerging pathogen.
View Article and Find Full Text PDFThe MinION sequencing platform offers near real-time analysis of DNA sequence; this makes the tool attractive for deployment in fieldwork or clinical settings. We used the MinION platform coupled to the NanoOK RT software package to perform shotgun metagenomic sequencing and profile mock communities and faecal samples from healthy and ill preterm infants. Using Nanopore data, we reliably classified a 20-species mock community and captured the diversity of the immature gut microbiota over time and in response to interventions such as probiotic supplementation, antibiotic treatment or episodes of suspected sepsis.
View Article and Find Full Text PDFHere, we describe the draft genome sequences of three strains of isolated from feces of preterm neonates with suspected sepsis. Strains P106E PI and P079F I were Strain P080C CL represents the first draft genome sequence of .
View Article and Find Full Text PDFHere, we describe the draft genome sequence of P079F W, isolated from the feces of an infant residing in a neonatal intensive care unit during an ongoing study to characterize the neonate gut microbiota. P079F W will be used in studies investigating the role of the microbiome in neonatal infections.
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