Publications by authors named "Thomas Breniere"

Article Synopsis
  • White adipose tissue (WAT) plays a crucial role in inflammation related to obesity and aging, as well as in the storage of vitamin D compounds.
  • The study measured levels of cholecalciferol and 25-hydroxyvitamin D (25(OH)D) in mice, finding that aging and obesity lead to lower plasma levels of these vitamins without significantly altering circulating inflammatory markers.
  • However, both aging and obesity increased inflammatory indicators in WAT, suggesting that the accumulation of vitamin D in this tissue may help mitigate inflammation linked to these conditions.
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Article Synopsis
  • Several studies suggest that lycopene and tomato products may enhance metabolic health, particularly in environments that promote obesity.
  • The research involved 80 male mice fed different diets supplemented with tomato powders from various genotypes, exploring their effects on obesity-related health issues.
  • Results showed that certain tomato genotypes improved fasting blood sugar and reduced liver fat, with one genotype (IL6-2) notably decreasing body weight and improving glucose levels, while irrigation levels had little effect on these health benefits.
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Aging and obesity are associated with a decrease in plasma 25-hydroxyvitamin D (25(OH)D) levels. In the context of a growing aging population and the rising incidence of obesity, we hypothesized that aging process, either independently or in combination with obesity, could influence vitamin D (VD) metabolism, consequently resulting in the reduced 25(OH)D plasma concentrations. C57BL/6JRJ young (6 months) and old (23 months) mice fed with control (CD) or high fat diet (HF) were compared.

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Article Synopsis
  • - Drought significantly impacts horticulture, particularly fruit quality and nutritional value, which has been less studied despite its importance.
  • - In a study analyzing six tomato genotypes and one goji cultivar under deficit irrigation (DI), it was found that DI increased certain health-related compounds, like phenolics and sugars, while negatively affecting ascorbic acid and decreasing total carotenoids in tomatoes.
  • - The study revealed that while DI concentrated some nutrients in the fruits, it did not always enhance their bioaccessibility, meaning that higher concentrations of metabolites did not guarantee better absorption in the body, varying by plant species and genotype.
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Article Synopsis
  • The narrative review examines the anti-inflammatory effects of tomatoes, tomato-based products, and lycopene, particularly regarding their connection to metabolic inflammation and cardiometabolic diseases.
  • * While animal studies and some human interventions suggest that tomatoes may help reduce metabolic inflammation, the results from various intervention studies are inconsistent.
  • * The review highlights the need for more research to better understand the differing effects of tomatoes, tomato products, and lycopene on inflammation in humans, noting existing limitations and gaps in the current knowledge.
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