Publications by authors named "Thomas Bourne"
Article Synopsis
- It involved a retrospective analysis of 377 sepsis cases from November 2018 to June 2021, revealing that AALs did not significantly impact the time to receive antibiotics or patient mortality rates.
- However, the presence of Emergency Medicine pharmacists led to quicker antibiotic administration and better appropriateness in antibiotic prescribing, suggesting their importance in sepsis management.
Introduction: The drive to achieving economy, efficiency and effective use of resources has catalysed the development of day case laparoscopic cholecystectomy (DCLC). The aims of this study were to determine the stay in (unplanned admission) rate of DCLC, identify reasons for unplanned admissions and re-admissions in this cohort of patients and explore how to improve the same day discharge rate.
Patients And Methods: This is a review of 258 patients undergoing DCLC between April 2008 and March 2009.
Beta-Arrestins act as signal terminators for G protein-coupled receptors; they have also been implicated as scaffolding proteins for Src and mitogen-activated protein kinase signaling pathways and transactivators of receptor tyrosine kinases, suggesting their possible role in development and oncogenic signaling. Dephosphorylation of serine 412 is necessary for Src and mitogen-activated protein kinase transactivation. We hypothesized that altered beta-arrestin 1 phosphorylation and activation status could play a role in gliomagenesis.
View Article and Find Full Text PDFObjectives: To evaluate the uptake and outcome of expectant management of spontaneous first trimester miscarriage in an early pregnancy assessment unit.
Participants: 1096 consecutive patients with a diagnosis of spontaneous first trimester miscarriage.
Methods: Each miscarriage was classified as complete, incomplete, missed, or anembryonic on the basis of ultrasonography.