Publications by authors named "Thomas Borchard"

Article Synopsis
  • People with neurodegenerative disorders often experience delays and misdiagnosis, making it important to find effective diagnostic tools.
  • This study compared levels of neurofilament light chain (NfL) in blood and cerebrospinal fluid (CSF) among individuals with neurodegenerative disorders (ND), primary psychiatric disorders (PPD), and healthy controls, showing that plasma NfL was significantly elevated in ND.
  • The research indicates that plasma NfL has strong diagnostic performance, especially in younger individuals, suggesting it could serve as a useful screening test to differentiate between ND and PPD in clinical settings.
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Substance use disorders are associated with diverse neuropsychological impairments, with deficits in memory and executive functioning commonly observed. Cognitive remediation has been shown to be effective in other populations with cognitive impairments in these domains, including those with psychiatric disorders and acquired brain injuries, and it has been hypothesised to be similarly effective for those in treatment for substance use disorders. We aimed to systematically review the evidence for cognitive remediation interventions administered as an adjunct treatment to substance use rehabilitation.

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