Publications by authors named "Thomas Andreas Thiel"
Purpose: To characterize the diffusion time (Δ) dependence of apparent diffusion coefficient (ADC) and intravoxel incoherent motion-related parameters in the human kidney at 3 T.
Methods: Sixteen healthy volunteers underwent an MRI examination at 3 T including diffusion-weighted imaging at different Δ ranging from 24.1 to 104.
Purpose: Development of a color scheme representation to facilitate the interpretation of tri-exponential DWI data from abdominal organs, where multi-exponential behavior is more pronounced.
Methods: Multi-exponential analysis of DWI data provides information about the microstructure of the tissue under study. The tri-exponential signal analysis generates numerous parameter images that are difficult to analyze individually.
Article Synopsis
- The study investigates the effectiveness of advanced MRI techniques, specifically UTE-T2* mapping, in accurately diagnosing posterior cruciate ligament (PCL) injuries compared to standard MRI methods.
- Ten human knee joint specimens were tested using various MRI sequences before and after performing controlled PCL injuries, measuring changes in T2* values and texture features related to ligament integrity.
- Results indicate that UTE-T2* mapping shows a significant increase in T2* values correlating with injury severity, suggesting it may enhance the ability to differentiate between partial and complete PCL injuries more effectively than conventional T2* mapping.
Based on in silico, in situ, and in vivo studies, this study aims to develop a new method for the quantitative chemical exchange saturation transfer (qCEST) technique considering multi-pool systems. To this end, we extended the state-of-the-art apparent exchange-dependent relaxation (AREX) method with a Lorentzian correction (LAREX). We then validated this new method with in situ and in vivo experiments on human intervertebral discs (IVDs) using the Kendall-Tau correlation coefficient.
View Article and Find Full Text PDFContrast-induced nephropathy (CIN) resembles an important complication of radiographic contrast medium (XCM) displayed by a rise in creatinine levels 48-72 h after XCM administration. The purpose of the current study was to evaluate microstructural renal changes due to CIN in high-risk patients by diffusion weighted (DWI) and diffusion tensor imaging (DTI). Fifteen patients (five CIN and ten non-CIN) scheduled for cardiological intervention were included in the study.
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