Publications by authors named "Thomas A Massaquoi"

The recent large outbreak of Ebola virus disease (EVD) in Western Africa resulted in greatly increased accumulation of human genotypic, phenotypic and clinical data, and improved our understanding of the spectrum of clinical manifestations. As a result, the WHO disease classification of EVD underwent major revision.

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Introduction: Hepatitis B is a serious public health problem across sub-Saharan Africa. Sierra Leone has no national hepatitis B strategy plan or high quality estimates of prevalence. Healthcare workers are perceived as an at-risk group for hepatitis B.

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Thousands of persons have survived Ebola virus disease. Almost all survivors describe symptoms that persist or develop after hospital discharge. A cross-sectional survey of the symptoms of all survivors from the Ebola treatment unit (ETU) at 34th Regimental Military Hospital, Freetown, Sierra Leone (MH34), was conducted after discharge at their initial follow-up appointment within 3 weeks after their second negative PCR result.

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Article Synopsis
  • Ebola virus RNA was detected in the semen of 27% of male survivors of Ebola virus disease in Sierra Leone, with varying detection rates depending on the time since discharge from treatment.
  • The study surveyed 220 male survivors with semen samples tested using RT-PCR methods, revealing a higher prevalence of viral RNA shortly after discharge and a significant decline over time.
  • The findings highlight the need for further research into the potential risks of sexual transmission of Ebola, as the study did not directly assess this aspect.
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