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Publications by authors named "Thomas A J McKinnon"

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Synopsis of recent research by authors named "Thomas A J McKinnon"

  • - Thomas A J McKinnon's recent research focuses on the interactions and mechanistic roles of von Willebrand factor (VWF) in hemostasis and thrombosis, emphasizing its significance in various vascular-related processes and conditions such as COVID-19 coagulopathy and multiple myeloma treatment.
  • - His findings reveal that specific factors, including the aptamer BT200 and the proteasome inhibitor carfilzomib, can influence VWF levels and endothelial functions, highlighting new therapeutic avenues for managing thrombotic disorders and cardiovascular risks associated with certain treatments.
  • - Additionally, McKinnon's work explores the molecular intricacies of VWF, including its interactions with other proteins in endothelial cells, and the impact of post-translational modifications like sialylation on its biological activity and plasma half-life.

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