Fine structure of GABAergic neurons and synapses in the human dentate gyrus.

Surgical tissue samples of the human dentate gyrus were immunostained for glutamate decarboxylase (GAD), the gamma-aminobutyric acid (GABA)-synthesizing enzyme, and studied by both light and electron microscopy. Immunoreactive neurons and terminals displayed similar morphological characteristics as known from studies in laboratory animals. Thus, GAD-positive neurons prevailed in the hilar region, whereas immunoreactive terminals were most frequently observed in the granular layer forming symmetric synaptic contacts with dendrites, cell bodies and axon initial segments of granule cells.

Sarcoidosis of the pineal gland. Case report.

The authors report a case of sarcoidosis of the pineal gland with no other organ manifestation of the disease. The tumor was successfully removed by a direct surgical approach.

[Operation results in 2000 cases of lumbar intervertebral disk lesions (author's transl)].

Operative treatment of lesions of the lumbar intervertebral disks with compression of the nerve roots is directed against the principal biomechanical cause of the clinical picture of the lumbosciatica. Very satisfactory results can be obtained if, besides the removal of the prolapsed portions of the disk in the intervertebral space, the diseased layer is also carefully cleared out as far as it is possible to do so, in the interests of preventing relapse. The operation should not be considered one for the inexperienced surgeon.