Minimally invasive glass-ceramic restorations: Clinical and patient-reported outcomes in full-mouth rehabilitations.

Objectives: To evaluate clinical outcomes (restoration survival, technical and biological complications), and patient-reported outcome measures (PROMs) of full mouth rehabilitation with minimally invasive glass-ceramic restorations after up to 12 years of clinical service.

Materials And Methods: Twenty individuals (12 females, 8 males) received full-mouth rehabilitation with minimally invasive tooth-supported glass-ceramic restorations during the years 2009 - 2017 and agreed to participate in a follow-up visit. Full dental and periodontal examinations were completed, and the restorations were evaluated according to United States Public Health Service (USPHS) criteria.

Bone Regeneration After Sinus Floor Elevation in an Intact Sinus or a Sinus With Prior Large Membrane Perforation: A Preclinical Study Using a Rabbit Sinus Model.

Aim: To determine bone regeneration following sinus floor elevation (SFE) at sites with or without prior sinus membrane perforation.

Materials And Methods: The sinus membranes in the maxillary sinuses of 12 rabbits were intentionally perforated (≥ 5 mm) on one side, followed by application of a collagen matrix. SFE was performed on both sinuses after 8 weeks of healing, presenting two groups: SFE with a previous large sinus membrane perforation (group SFE_Perf), and in an intact sinus (group SFE).

Long-term clinical and radiographic outcomes of a bone-level, 2-piece, internal connection implant system with coronal microthreads over 10 years of follow-up: a retrospective clinical study.

Purpose: This study retrospectively investigated the long-term clinical and radiographic outcomes of a bone-level type, 2-piece, internal connection dental implant system characterized by coronal microthreads.

Methods: A total of 872 implants placed in 284 patients were selected from 1,845 implants placed in 691 patients by experienced periodontists at Yonsei University Dental Hospital. These selected implants had been followed up for over 10 years and were included in the present study.

Rehabilitation of the Worn Dentition With Direct and Indirect Minimally Invasive Concepts-A Systematic Review and Meta-Analysis.

Objective: To report and compare the survival of minimally invasive direct and indirect restorations of different materials for restoring the worn dentition.

Material And Methods: A systematic search was conducted in six databases: MEDLINE, Web of Science, Scopus, CENTRAL, VHL, and EMBASE. The eligibility criteria of this systematic review used the PICO framework to address the following research question: "In dentate patients with a worn dentition (P), does rehabilitating their lost tooth structure with indirect restorations (I) or direct (C) effect the survival and success of treatment (O)?".

Effects of Polydeoxyribonucleotide (PDRN) on Endosinus Bone Regeneration Following Sinus Floor Elevation: An Experimental In Vivo Pilot Study.

Objective: To determine the effect of polydeoxyribonucleotide (PDRN) on endosinus bone regeneration in a rabbit sinus model at sequential healing time points.

Materials And Methods: Eighteen New Zealand white rabbits were used. Bilateral sinus floor elevation (SFE) was performed.

Preclinical Investigation on the Effect of Collagen Matrix With Polydeoxyribonucleotide at Buccally Positioned Implants.

Objectives: The objective of this study is to investigate the effect of collagen matrix with polydeoxyribonucleotide (PDRN) at two concentrations on keratinized tissue (KT) regeneration for buccally positioned implants in canines.

Methods: Four implants were placed in the edentulous mandible of five dogs simultaneously with KT removal. The implants were positioned buccally with respect to the ridge crest.

Comparing Small Buccal Dehiscence Defects Treated with or without Guided Bone Regeneration. A Sub-Analysis of a RCT.

Aim: to assess clinical and radiographical outcomes of single tooth posterior implants with a dehiscence defect treated with or without guided bone regeneration (GBR).

Methods: In a randomized clinical trial of 59 patients, single-tooth posterior implants were placed. For the subanalysis of 16 patients with a buccal dehiscence defect (≤ 5mm), the implants were randomly assigned to GBR or spontaneous healing (SH).

Soft Tissue Contours at Pontic Sites With or Without Soft Tissue Grafting-A 15-Year Follow-Up of a Controlled Clinical Study.

Objectives: To report on soft tissue contour changes at pontic sites with or without soft tissue grafting over an observation period of 15 years.

Methods: Fourteen patients received a fixed dental prosthesis (FDP) in the posterior zone in a controlled clinical study and were available at the 15-year follow-up. Eight patients received a subepithelial connective tissue graft in the pontic area (test) while six received the FDP without soft tissue grafting (control).

Maintenance Costs, Time, and Efforts Following Implant Therapy With Fixed Restorations Over an Observation Period of 10 Years: A Randomized Controlled Clinical Trial.

Objectives: To assess the costs and efforts of maintenance therapy following implant treatment with fixed restoration over an observation period of 10 years.

Material And Methods: This randomized controlled clinical trial included 64 patients who were randomly assigned to receive one of two implant systems (AST or STM) and fixed restoration. Patients were included in a regular maintenance program and were examined at loading, 1, 3, 5, 8, and 10 years.

Effects of hard- and/or soft-tissue grafting with early implant placement: Histomorphometric outcomes of an exploratory study in canines.

Objective: To histomorphometrically determine the effects of hard- and/or soft-tissue augmentation by applying the early implant placement protocol.

Materials And Methods: The distal roots of the maxillary second and third premolars were extracted in 10 mongrel dogs. After 1 month, early implant placement was performed in the distal roots, resulting in buccal dehiscence defects.

Homophone priming in bilingual preference formation.

Homophone (HP) priming occurs when phonologically ambiguous words persistently coactivate their contextually irrelevant meanings. If suppressing those meanings fails, they subliminally bias preferences. Yet, it is unclear if prior findings generalize beyond individual words and to bilingual contexts.

A 7.5-year randomized controlled clinical study comparing cemented and screw-retained one-piece zirconia-based implant-supported single crowns.

Objectives: To compare marginal bone levels, biological, and technical outcomes of screw-retained versus cemented all-ceramic implant-supported zirconia-based single crowns after an observation period of 7.5 years.

Methods: Forty-four single implants in the esthetic zone in 44 patients (22 females, 22 males) were randomly assigned to two types of restorations: SR (screw-retained); veneered one-piece zirconia abutment and CR (cement-retained); veneered lithium disilicate crown intraorally cemented on a one-piece zirconia abutment.

Clinical outcomes of single implant supported crowns utilising the titanium base abutment: A 7.5-year prospective cohort study.

Objective: To assess radiographic, clinical and patient-reported outcomes of single zirconia implant-supported crowns on titanium base abutments (TBA) over a 7.5-year period.

Methods: Twenty-four patients received bone-level titanium implants and screw-retained zirconia implant crowns utilising TBA.

3D surface defect map for assessing buccolingual profile of single tooth gaps following alveolar ridge preservation.

Aim: A new, non-invasive approach suggests using single intraoral optical scanning to analyze the ridge profile of single-tooth gaps following alveolar ridge preservation in the absence of a baseline scan. This method involves creating a three-dimensional (3D) surface map to identify and assess contour changes and ridge profiles based on the adjacent teeth.

Materials And Methods: The present study was designed as a cross-sectional pilot analysis on a convenience sample of patients undergoing alveolar ridge preservation.

Effect of Membrane Fixation and the Graft Combinations on Horizontal Bone Regeneration: Radiographic and Histologic Outcomes in a Canine Model.

The aim of this study was to determine the effect of membrane fixation and combinations of bone substitute materials and barrier membranes on horizontal bone regeneration in peri-implant defects. Eight mongrel dogs underwent chronic buccal peri-implant dehiscence defects creation and were randomized into 4 groups: (a) deproteinized bovine bone mineral 1 (DBBM1) with a native collagen membrane (CM) (BB group, positive control group), (b) DBBM1 with native CM and 2 fixation pins (BBP group), (c) DBBM2 with a cross-linked CM (XC group), and (d) DBBM2 with cross-linked CM and 2 fixation pins (XCP group). Following 16 weeks of healing, tissues were radiographically and histomorphometrically analyzed.

Clinical, radiographic and patient-reported outcomes of zirconia and titanium implants in the posterior zone after 1 year of loading-A randomized controlled trial.

Objective: To assess the clinical, radiographic and patient-reported outcomes (PROMs) of posterior zirconia and titanium implants at 1 year of implant loading.

Materials And Methods: Forty-two patients with two adjacent missing teeth were enrolled in a randomized controlled trial with a within-subject controlled design. Each patient received one zirconia (Zr) and one titanium (Ti) implant, with the mesial and distal positions randomized.

Early implant placement versus ridge preservation and delayed implant placement: Analysis of profilometric, clinician- and patient-reported outcomes from a two-centre RCT.

Objectives: To compare early implant placement (EP) to alveolar ridge preservation and delayed implant placement (ARP/DP) in terms of contour changes, along with clinician- and patient-reported outcome measures (PROMs) until the delivery of the implant-supported restoration.

Materials And Methods: Patients with a failing single tooth in the maxilla or mandible were recruited in two centres. After tooth extraction, patients were randomly assigned (1:1) to either EP or ARP/DP.

Does an untreated peri-implant dehiscence defect affect the progression of peri-implantitis?: A preclinical in vivo experimental study.

Objective: To investigate the early impact of plaque accumulation in a buccal dehiscence defect on peri-implant marginal bone resorption.

Materials And Methods: In six male Mongrel dogs, four dental implants were placed in the posterior maxilla on both sides (two implants per side). Based on the group allocation, each implant was randomly assigned to one of the following four groups to decide whether buccal dehiscence defect was prepared and whether silk ligation was applied at 8 weeks post-implant placement for peri-implantitis induction: UC (no defect without ligation); UD (defect without ligation); LC (no defect with ligation); and LD (defect with ligation) groups.

Enhancing guided bone regeneration with cross-linked collagen-conjugated xenogeneic bone blocks and membrane fixation: A preclinical in vivo study.

Objective: To determine whether combining cross-linked (CL) collagen-integrated xenogeneic bone blocks stabilized with the fixation of resorbable collagen membranes (CM) can enhance guided bone regeneration (GBR) in the overaugmented calvarial defect model.

Materials And Methods: Four circular defects with a diameter of 8 mm were prepared in the calvarium of 13 rabbits. Defects were randomly assigned to receive one of the following treatments: (i) non-cross-linked (NCL) porcine-derived collagen-embedded bone block covered by a CM without fixation (NCL + unfix group); (ii) NCL bone block covered by CM with fixation using bone-tack (NCL + fix group); (iii) cross-linked (CL) porcine-derived collagen-embedded bone block covered by CM without fixation (CL + unfix group); and (iv) CL bone block covered by CM with fixation using bone-tack fixation (CL + fix group).

Immediate loading of definitive restorations in partially edentulous patients requiring an implant-supported prosthesis: A scoping review.

Statement Of Problem: Interest is growing in immediately loading definitive implant-supported prostheses. However, it appears that implant protocols are evolving faster than their scientific validation.

Purpose: The purpose of this scoping review was to identify the current trends, feasibility, and clinical outcomes of a specific clinical loading scenario (type A), where a single definitive implant-retained restoration is delivered within 3 days.

Immediate loading on two adjacent single dental implants with definitive nonsplinted restorations: A proof of concept in the posterior zone.

Objectives: To evaluate clinical, clinician- and patient-reported outcomes (PROs) of two adjacent single posterior implants immediately loaded with definitive single crowns up to 1 year. Ten patients in need of two adjacent posterior single implants were included. All implants were placed applying a fully digital workflow.

Effects of implant placement timing and type of soft-tissue grafting on histological and histomorphometric outcomes in a preclinical canine model.

Aim: To determine the effects of implant timing and type of soft-tissue grafting on histological and histomorphometric outcomes in a preclinical model.

Materials And Methods: Four implant placement protocols were randomly applied at the mesial root sites of the third and fourth mandibular premolars in 10 mongrel dogs: immediate placement (group IP), early placement (group EP), delayed placement with/without alveolar ridge preservation (groups ARP and DP, respectively). A connective-tissue graft (CTG) or porcine-derived volume-stable collagen matrix (VCMX) was applied to enhance the ridge profile (simultaneously with implant placement in group IP and staged for others), resulting in five sites for each combination.

Impact of keratinized mucosa on implant-health related parameters: A 10-year prospective re-analysis study.

Aim: To investigate whether the lack of keratinized mucosa (KM) affects peri-implant health after 10 years of loading.

Materials And Methods: Data from 74 patients with 148 implants from two randomized controlled studies comparing different implant systems were included and analyzed. Clinical parameters including bleeding on probing (BOP), probing depth (PD), plaque index, marginal bone loss (MBL), and KM width (KMW) at buccal sites were collected at baseline (time of the final prosthesis insertion), 5-year and 10 years postloading.