Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration.

Objective: To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women.

Methods: We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy postpartum women who delivered vaginally. After oral administration of 2 g of immediate-release tranexamic acid 1 hour after delivery, pharmacokinetic parameters were measured on plasma samples at 0, 0.