Publications by authors named "Thitikarn Lerthiranwong"

Objective: To compare the predictive performance in differentiating benign from malignant ovarian masses between the modified risk malignancy index (RMI) and the conventional RMI (RMI-1 and RMI-2).

Methods: Women scheduled for elective surgery because of adnexal masses were recruited to undergo pelvic sonography within 24 h before surgery to assess the sonographic characteristics of the masses, focusing on loculi, solid part, ascites, bilateralness, papillary projection, and color flow mapping (CFM). Preoperative CA-125 levels were also measured.

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Background The primary objective of this study was to compare the fetal cardiac performance index (Tei index) between the fetuses of gestational diabetes mellitus (GDM) mothers and non-GDM mothers; and the secondary objective was to compare various other parameters of fetal cardiac function as well as maternal oxidative stress levels between the groups of GDM and non-GDM mothers. Methods A cross-sectional study was conducted on pregnant women at 24-28 weeks of gestation. All of the participants underwent 100 g, 3-h oral glucose tolerance test (OGTT) as a diagnostic test for GDM and were categorized as non-GDM and GDM group.

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Article Synopsis
  • This study aimed to evaluate how well the International Ovarian Tumor Analysis (IOTA) simple rules compared to the Risk of Malignancy Index (RMI 1/RMI 2) in identifying whether adnexal masses are benign or malignant.
  • Out of 479 evaluated adnexal masses, IOTA rules effectively assessed 81.8% of them, showing higher sensitivity (83.8%) and specificity (92.0%) than both versions of RMI, which had lower percentages.
  • Although IOTA showed better diagnostic accuracy, nearly 20% of its assessments were inconclusive, indicating that expert consultation was often needed for those cases.
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Maternal autoantibodies to Ro/SSA are often linked to congenital heart block and rarely associated with structural defects. We describe the case of a fetus with anti-Ro-mediated second-degree block at 19 weeks, which progressed to a complete block, fibroelastosis, atrioventricular valve insufficiency, and semilunar valve stenosis/insufficiency at 20, 22, 24, and 26 weeks, respectively, although the fetus received transplacental anti-arrhythmic drugs. The 2150-g fetus was vaginally delivered at 35 weeks.

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Article Synopsis
  • The study aimed to evaluate the effectiveness of first-trimester maternal serum screening (MSS) for detecting Down syndrome in Thai women using either Caucasian reference ranges with racial factor correction or Thai-specific reference ranges.
  • Results showed that using Thai reference ranges resulted in a significantly higher detection rate (77.8%) and lower false-positive rate (7.5%) for Down syndrome compared to the Caucasian method (63.9% detection rate and 12.5% false positives).
  • The findings highlight that using locally relevant reference ranges significantly improves screening accuracy, emphasizing the importance of considering ethnic differences in screening methods.
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Background: To compare diagnostic performance in differentiating benign from malignant ovarian masses between IOTA (the International Ovarian Tumor Analysis) simple rules and subjective sonographic assessment.

Materials And Methods: Women scheduled for elective surgery because of ovarian masses were recruited into the study and underwent ultrasound examination within 24 hours of surgery to apply the IOTA simple rules by general gynecologists and to record video clips for subjective assessment by an experienced sonographer. The diagnostic performance of the IOTA rules and subjective assessment for differentiation between benign and malignant masses was compared.

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Objective: To evaluate the diagnostic performance of IOTA simple rules in predicting malignant adnexal tumors by non-expert examiners.

Materials And Methods: Five obstetric/gynecologic residents, who had never performed gynecologic ultrasound examination by themselves before, were trained for IOTA simple rules by an experienced examiner. One trained resident performed ultrasound examinations including IOTA simple rules on 100 women, who were scheduled for surgery due to ovarian masses, within 24 hours of surgery.

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