Potential of dual time point FDG-PET imaging in differentiating malignant from benign pleural disease.

Aim: The aim of this study was to assess the utility of dual time point 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) imaging in differentiating benign from malignant pleural disease.

Methods: Fifty-five consecutive patients of suspected malignant pleural mesothelioma (MPM) and recurrence of MPM who were referred for the evaluation underwent two sequential 18F-FDG-PET scans (dual time point imaging). The average percent change in the maximum standardized uptake values (Delta%SUVmax) of the lesion/lesions between time point 1 (SUV(max1)) and time point 2 (SUV(max2)) was calculated.

A recovery coefficient method for partial volume correction of PET images.

Objectives: Correction of the "partial volume effect" has been an area of great interest in the recent times in quantitative PET imaging and has been mainly studied with count recovery models based upon phantoms that incorporate hot spheres in a cold background. The goal of this research study was to establish a similar model that is closer to a biological imaging environment, namely hot spheres/lesions in a warm background and to apply this model in a small cohort of patients.

Methods: A NEMA phantom with six spheres (diameters 1-3.

Follow-up FDG PET in the evaluation of unexplained focal activity in the abdomen.

Purpose: This study assessed the value of a follow-up FDG PET scan when the initial PET demonstrated unexplained findings of focal FDG uptake in the abdomen.

Method: The records of 3634 patients with PET scans were retrospectively reviewed. Those patients who had follow-up PET scans after the initial PET scan showed unexplained FDG activity in the abdomen were further analyzed.

Dual-time point FDG PET imaging in the evaluation of pulmonary nodules with minimally increased metabolic activity.

Purpose: FDG PET has high accuracy in the evaluation of lung nodules. A standardized uptake value (SUV) > or =2.5 is frequently used as a criterion for malignancy in this setting.

Dual time point 18F-FDG PET imaging detects breast cancer with high sensitivity and correlates well with histologic subtypes.

Unlabelled: This prospective study was designed to assess the utility of the dual time point imaging technique by (18)F-FDG PET in detecting primary breast cancer and to determine whether there is a relationship between (18)F-FDG uptake and its change over time and the histopathologic subtypes.

Methods: One hundred fifty-two patients with newly diagnosed breast cancer underwent 2 sequential PET scans (dual time point imaging) for preoperative staging. The maximum standardized uptake value (SUVmax) of (18)F-FDG was measured from both time points.

Intense esophageal FDG activity caused by Candida infection obscured the concurrent primary esophageal cancer on PET imaging.

Esophageal cancer frequently causes a focal intense FDG uptake on positron emission tomography (PET) imaging while esophagitis often results in a mild to moderate degree of FDG activity in a diffuse pattern. However, detection of an esophageal cancer can become difficult in the presence of a diffuse esophageal activity because of esophagitis. We present such case in which esophageal cancer superimposed by Candidal esophagitis is difficult to recognize on FDG PET images.