Adolescent prolapsed lumbar intervertebral disc: Management strategies and outcome.

Objective: Lumbar intervertebral disc herniation (LIVDH) is rare in children and adolescents when compared to adults. In literature, children generally constitute around 0.5-3% of surgically treated LIVDH.

Rapid characterization of molecular diffusion by NMR spectroscopy.

An NMR-based approach for rapid characterization of translational diffusion of molecules has been developed. Unlike the conventional method of acquiring a series of 2D (13)C and (1)H spectra, the proposed approach involves a single 2D NMR spectrum, which can be acquired in minutes. Using this method, it was possible to detect the presence of intermediate oligomeric species of diphenylalanine in solution during the process of its self-assembly to form nanotubular structures.

Accessing the disallowed conformations of peptides employing amide-to-imidate modification.

Selective modification of the C-terminal amide in peptides to dihydrooxazine (a novel stable imidate isostere) by intramolecular nucleophilic cyclo-O-alkylation of the corresponding N-(3-bromopropyl)amides results in constraining of the C-terminal residue in natively disallowed conformations both in crystals and in solution.

Spontaneous and reversible self-assembly of a polypeptide fragment of insulin-like growth factor binding protein-2 into fluorescent nanotubular structures.

In this communication, we report the spontaneous and reversible in vitro self-assembly of a polypeptide fragment derived from the C-terminal domain of Insulin-like Growth Factor Binding Protein (IGFBP-2) into soluble nanotubular structures several micrometres long via a mechanism involving inter-molecular disulfide bonds and exhibiting enhanced fluorescence.

N-{1-[(3-Bromo-prop-yl)amino-carbon-yl]eth-yl}-2-(2-nitro-benzene-sulfonamido)propionamide.

In the title compound, C(15)H(21)BrN(4)O(6)S, all three NH groups are involved in inter-molecular N-H⋯O inter-actions which, together with two inter-molecular C-H⋯O contacts, lead to a continuous anti-parallel β-sheet structure. There are no π-π inter-actions between mol-ecules, and two C-H⋯π inter-actions primarily govern the linkage between sheets.

Sparing effect of tendon injury on osteoarthritis.

A case is reported in which a finger with no active flexion did not develop erosive osteoarthritis at the time that it developed in the other active digits.

Rupture of the triceps tendon with olecranon bursitis. A case report with a new method of repair.

Rupture of the triceps tendon is rare, and no previous report of its association with olecranon bursitis was found in the literature. A previously healthy 72-year-old man fell from a stationary bicycle and was examined by his family physician. Calcification over the olecranon area with an intact triceps tendon was revealed.

Dorsal wrist synovectomy in rheumatoid arthritis--a long-term study.

Dorsal wrist synovectomy, tenosynovectomy of the extensor tendons, excision of the distal ulna, ulnar-side stabilization of the wrist, and placement of the extensor retinaculum underneath the extensor tendons is an effective procedure in wrists with rheumatoid arthritis. Twenty-seven patients who had surgery on 38 wrists were followed for 5 to 14 years, with an average of 7.4 years.

Desmoplastic fibroma of the ulna. A case report.

This report of desmoplastic fibroma of bone (DFB) in the left ulna represents the 56th published case of the neoplasm. To the best of the authors' knowledge, the present case is the first instance of this type of excision of the distal ulna performed for DFB with a metallic prosthesis and successful restoration of distal radial ulnar anatomy and function.

Failure of polyethylene acetabular cups. Two case reports.

Fatigue fracture involving the metallic femoral stem is well recognized after total hip arthroplasty. Two cases of Charnley-Mueller polyethylene acetabular cup failure, in a 54-year-old-woman and a 77-year-old woman with abnormal wear patterns, were diagnosed prior to operation. The fracture of the acetabular cup was recognized by the fragmented, crushed appearance of the cup.

Dislocation following total hip arthroplasty. Management by special brace in selected patients.

Dislocation after total hip arthroplasty (THA) occurs in 1%-3% of the cases reported in the literature. Recurrent dislocations due to malpositioned components should be treated by revision arthroplasty. Dislocated hips that have optimally positioned components but weak abductors can be treated by a special brace that prevents extremes of flexion, adduction, and rotation.

Extensor tendon rupture over the metacarpal heads.

Rupture of the extensor tendons is common in longstanding rheumatoid arthritis of the hand. The tendons commonly involved are those of the ring and little fingers and the common site of rupture is over the dorsal ulna and distal edge of the extensor retinaculum. We are reporting two cases of extensor tendon rupture over the metacarpal head of the middle finger due to prominent osteophytes.

The Jeweller's Thumb: An Occupational Neuroma A Case Report.

Perineural fibrosis and scarring of superficial nerves can occu r secondary to chronic frictional forces. This results in a tender lump in the nerve and hyperesthesia of the area of its distribution. Bowler's thumb is a well known entity which involves the ulna side digital nerve of the thumb at the level of the MP joint.

Patellar complications after total condylar arthroplasty.

The incidence of complications in the initial three years' experience with total knee arthroplasty and patellar replacement was 9%. Of the total knee arthroplasties perforated in the last three years, neither fracture nor subluxation of the patella has occurred. A prosthesis with right and left femoral components and slight lateral (physiologic) slanting of the patellar groove is recommended.

Traumatic disruption of the manubriosternal joint. A case report.

A case of manubriosternal dislocation is presented. The possible mechanism of injury was hyperflexion of the spine which resulted in chin to chest contact, disrupting the manubriosternal joint. If the dislocation is Type I and the patient has compression symptoms on the trachea or major vessels, surgical treatment by wiring may be needed.