Publications by authors named "Thiruneelakandan Sambanthan"

Endodontic-periodontal (endo-perio) lesions are commonly encountered in dental clinics, with patients typically presenting with acute pulpal pain, often accompanied by abscess formation and tooth mobility. Management generally involves root canal treatment (RCT) and, if required, surgical intervention. This article discusses a notable case of a 43-year-old male patient who presented with a chief complaint of pain and loose teeth in the upper left back region for the past 3 weeks.

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Context: The epithelium atrophy, as the oral submucous fibrosis (OSMF) progresses, is believed to be an after effect of stromal fibrosis, hyalinization, decrease in vascularity and cellularity and is considered as "ischemic atrophy." Due to hypoxia, caspase-3 get activation and subsequent decrease in viable cell count can occur.

Aims And Objectives: To determine caspase-3 expression in various grades of OSMF and oral squamous cell carcinoma (OSCC) to find out whether upregulation of apoptosis is responsible for the epithelial changes in OSMF.

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