Publications by Thirumaleswara Goud

Publications by authors named "Thirumaleswara Goud"

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Altered pharmacokinetics and pharmacodynamics of repaglinide by ritonavir in rats with healthy, diabetic and impaired hepatic function.

Thirumaleswara Goud Srinivas Maddi Devanna Nayakanti Rajendra Prasad Thatipamula

Drug Metab Pers Ther

June 2016

Background: Ritonavir is an antiretroviral drug to treat HIV AIDS and inhibits cytochrome P450 3A4. To treat diabetes mellitus in HIV, repaglinide is coadministered with ritonavir in the clinic. Multiple cytochrome P450 (CYP) isoforms are involved in the metabolism of repaglinide like CYP2C8 and CYP 3A4.

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