Publications by authors named "Thirumalai Arunagiri"
Corrective and preventive actions (CAPA) are crucial components of quality assurance (QA) within the pharmaceutical industry, essential for maintaining product quality, safety, and regulatory compliance. The review explores the multifaceted role of CAPA in pharmaceutical manufacturing, emphasizing its structured approach to detecting, addressing, and preventing quality issues. CAPA systems are integral to the broader quality management system (QMS), functioning as a dual-loop mechanism that is reactive and proactive approach aligned with continuous improvement principles outlined by the International Organization for Standardization (ISO) 9001:2000.
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- Monkeypox (Mpox) has evolved from a localized threat in Africa since 1970 to a global concern, with an outbreak in 2022 and ongoing cases in several African countries.
- The monkeypox virus (MPXV) poses significant public health challenges due to its mutation rate and ability to evade immune responses, necessitating global surveillance and research for effective prevention strategies.
- The study emphasizes understanding MPXV's history, complexity, and the role of circadian rhythms in virus replication to inform better control methods and address drug-resistant mutations.
Article Synopsis
- * The study draws from literature, patient insights, and healthcare professionals to highlight the complexities of diagnosing Mpox, particularly during its global spread.
- * Various diagnostic techniques are explored, with quantitative polymerase chain reaction (qPCR) identified as the primary method for detecting monkeypox, emphasizing the need for accurate diagnosis and efficient testing to contain the virus.
Mpox treatment evolution: past milestones, present advances, and future directions.
Naunyn Schmiedebergs Arch Pharmacol
September 2024
An underestimated worldwide health concern, Monkeypox (Mpox) is becoming a bigger menace to the world's population. After smallpox was eradicated in 1970, Mpox was found in a rural region of Africa and quickly spread to other African countries. The etiological agent of the Mpox infection, the Mpox virus, is constantly evolving, and its capability for cross-species transmission led to a global outbreak in 2022 which led to several deaths throughout the world.
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