Publications by authors named "Thijs Perik"

Over the last few years, magnetic resonance image-guided radiotherapy systems have been introduced into the clinic, allowing for daily online plan adaption. While quality assurance (QA) is similar to conventional radiotherapy systems, there is a need to introduce or modify measurement techniques. As yet, there is no consensus guidance on the QA equipment and test requirements for such systems.

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We developed and validated a dedicated small field back-projection portal dosimetry model for pretreatment andverification of stereotactic plans entailing small unflattened photon beams. For this purpose an aSi-EPID was commissioned as a small field dosimeter. Small field output factors for 6 MV FFF beams were measured using the PTW microDiamond detector and the Agility 160-leaf MLC from Elekta.

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Purpose: Despite their availability and simplicity of use, Electronic Portal Imaging Devices (EPIDs) have not yet replaced detector arrays for patient specific QA in 3D. The purpose of this study is to perform a large scale dosimetric evaluation of transit and non-transit EPID dosimetry against absolute dose measurements in 3D.

Methods: After evaluating basic dosimetric characteristics of the EPID and two detector arrays (Octavius 1500 and Octavius 1000 ), 3D dose distributions for 68 VMAT arcs, and 10 IMRT plans were reconstructed within the same phantom geometry using transit EPID dosimetry, non-transit EPID dosimetry, and the Octavius 4D system.

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Background And Purpose: External dosimetry audits are powerful quality assurance instruments for radiotherapy. The aim of this study was to implement an electron dosimetry audit based on a contemporary code of practice within the requirements for calibration laboratories performing proficiency tests. This involved the determination of suitable acceptance criteria based on thorough uncertainty analyses.

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Recently flattening filter free (FFF) beams became available for application in modern radiotherapy. There are several advantages of FFF beams over conventional flattening filtered (cFF) beams, however differences in beam spectra at the point of interest in a phantom potentially affect the ion chamber response. Beams are also non-uniform over the length of a typical reference ion chamber and recombination is usually larger.

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Purpose: To systematically evaluate machine specific quality assurance (QA) for volumetric modulated arc therapy (VMAT) based on log files by applying a dynamic benchmark plan.

Methods And Materials: A VMAT benchmark plan was created and tested on 18 Elekta linacs (13 MLCi or MLCi2, 5 Agility) at 4 different institutions. Linac log files were analyzed and a delivery robustness index was introduced.

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