Publications by authors named "Thijs L Braber"
Article Synopsis
- * Researchers analyzed the data from 289 participants over a follow-up period of about 6.3 years, finding that the prevalence of CAC and the median CAC score increased significantly during this time.
- * Results suggested that vigorous exercise intensity might reduce the increase in CAC scores, while very vigorous intensity exercise could actually lead to a greater increase in those scores, indicating a complex relationship between exercise intensity and coronary health.
Article Synopsis
- Recent studies suggest that while transradial access (TRA) is preferred for complex coronary procedures, many patients still require femoral access, especially for chronic total occlusions (CTO), and using ultrasound for puncture may reduce complications.
- A study involving 542 patients is designed to compare ultrasound-guided puncture and fluoroscopy-guided puncture for accessing the femoral artery during complex PCI, focusing on access site complications and major adverse cardiovascular events.
- Ethical approval has been obtained from multiple committees, and the outcomes of the trial will be shared in peer-reviewed journals, with details available on ClinicalTrials.gov under identifier NCT03846752.
Background: Higher levels of physical activity are associated with a lower risk of cardiovascular events. Nevertheless, there is debate on the dose-response relationship of exercise and cardiovascular disease outcomes and whether high volumes of exercise may accelerate coronary atherosclerosis. We aimed to determine the relationship between lifelong exercise volumes and coronary atherosclerosis.
View Article and Find Full Text PDFBackground: Most exercise-related cardiac arrests in men aged ≥45 years are due to coronary artery disease (CAD). The current sports medical evaluation (SME) of middle-aged sportsmen includes medical history, physical examination and resting and exercise electrocardiography (ECG). We investigated the added value of low-dose cardiac computed tomography (CCT) - both non-contrast CT for coronary artery calcium scoring (CACS) and contrast-enhanced coronary CT angiography (CCTA) - in order to detect occult CAD in asymptomatic recreational sportsmen aged ≥45 years without known cardiovascular disease.
View Article and Find Full Text PDFObjective: This study aims to evaluate whether coronary calcium scoring (CCS) is also feasible using low-radiation-dose coronary computed tomography angiography (CCTA) in combination with iterative reconstruction.
Methods: Forty-three individuals without known coronary artery disease underwent both noncontrast CCS (±1 mSv) for reference Agatston scores and low-dose CCTA (±3 mSv). Raw CCTA data were reconstructed with filtered back projection (FBP), hybrid iterative reconstruction (HIR), and model-based iterative reconstruction (MIR).
Background: Cardiovascular screening may benefit middle-aged sportsmen, as coronary artery disease (CAD) is the main cause of exercise-related sudden cardiac death. Arterial stiffness, as measured by pulse wave velocity (PWV), may help identify sportsmen with subclinical CAD. We examined the additional value of PWV measurements to traditional CAD risk factors for identifying CAD.
View Article and Find Full Text PDFWe report a case with a hypersensitivity reaction to clopidogrel that resolved after clopidogrel discontinuation and recurred on rechallenge. The reaction included fever, tachycardia, rash and mild angioedema. As an alternative to clopidogrel, the more potent thienopyridine prasugrel was administered without any signs of an allergic reaction in the hours, days and weeks following administration.
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