Publications by authors named "Thijs J"

Socioeconomic status (SES) predicts many facets of preadolescents' life opportunities, yet little is known about how children perceive SES and whether it plays a role in their group evaluations. This study examined preadolescents' socioeconomic understandings and biases (investigated presenting fictitious peers varying in SES), while separating the three SES-indicators income, education and occupation. Five classes (Grade 4-6) with 89 students (Mage = 10.

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Although there have been numerous studies on the relations between group identification and ethnic prejudice, it is less clear whether their associations reflect stable individual tendencies or rather situational or temporal fluctuations. This longitudinal multilevel study aimed to fill this gap by examining the between- and within-person associations of identification with the national and superordinate human groups and levels of prejudice against multiple ethnic minorities. A total of 883 Italian majority adolescents (M = 15.

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Atopic dermatitis (AD) is a chronic inflammatory skin disease for which new targeted therapies are currently available. Due to the increased rates of ocular surface disease (OSD) reported during treatment with these new targeted treatments, more insight into the occurrence and pathomechanism of OSD in moderate-to-severe AD patients is needed. Therefore, this review's first part highlights that most patients with moderate-to-severe AD already have characteristics of OSD before starting targeted treatment.

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Introduction: Ethnic prejudice poses a great challenge to the cohesion of current multicultural societies. Prior research has found that media portrayals of immigration-related issues might skew individual attitudes and feelings toward ethnic minorities. While these studies have focused on negative representations of ethnic minorities, less is known about the effects of media reports of unfortunate events affecting the victims of war, as in the case of the Ukrainian group in the Russia-Ukraine war.

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This longitudinal study (three waves across a school year) investigated the links between children's motivations to respond without prejudice and their ethnic outgroup attitudes at the between-person level (means and changes over time) and the within-person level (time-specific fluctuations). Participants were 945 ethnic majority students ( = 9.86 years, = 1.

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The influence of group norms is often tested via people's norm perceptions. Yet, people's group norm perceptions can be inaccurate, which raises the question to what extent effects of perceived norms indicate real group influence. The present study sought to obtain a better understanding of the value of group norm perceptions in social influence research.

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Background: Dupilumab-associated ocular surface disease (DAOSD) is frequently reported as side effect in atopic dermatitis (AD) patients. Therefore, the aim of this study was to investigate the frequency and severity of DAOSD, ophthalmic treatment response and to learn more about the effect of dupilumab on conjunctival goblet cells (GC).

Methods: This prospective study included dupilumab-treated AD patients between February 2020 and June 2022 from the University Medical Centre Utrecht.

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Severe uveitis is a rare complication of interleukin-4 receptor alpha blocking by dupilumab in topic dermatitis (AD) patients. The aim of this study was to describe five moderate-to-severe AD patients who developed uveitis during dupilumab treatment and to compare the proteomic profile of aqueous humor (AqH) of dupilumab-associated uveitis (n=3/5 available samples) with non-infectious uveitis (n=27) and cataract controls (n=11). Included patients were treated at the University Medical Center Utrecht (the Netherlands).

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Atopic dermatitis (AD) is a complex and highly heterogeneous inflammatory skin disease. Given the highly heterogeneous character of AD, it is unlikely that every patient will respond equally to a particular treatment. The recent introduction of novel targeted therapies for AD has driven the need for patient stratification based on immunologic biomarkers.

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This research examined the preference for identity-first language (IFL) versus person-first language (PFL) among 215 respondents (M = 30.24 years, SD = 9.92) from the Dutch autism community.

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Background: The patho-mechanism of ocular surface disease (OSD) in dupilumab-treated atopic dermatitis (AD) patients remains unclear. The aim of this study is to measure dupilumab levels in tear fluid and serum, and relate these findings to the severity of OSD during dupilumab treatment in AD patients.

Methods: This prospective study included dupilumab-treated moderate-to-severe AD patients who were seen by a dermatologist and an ophthalmologist before the start of dupilumab (baseline), and after 4 and 28 weeks of dupilumab treatment.

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Article Synopsis
  • The study focuses on patients with atopic dermatitis (AD) undergoing treatment with dupilumab, aiming to investigate the relationship between serum levels of dupilumab at 16 weeks and both treatment response and adverse effects.
  • Conducted at the University Medical Center Utrecht, the research involved 295 adult patients treated according to a specific clinical protocol, excluding those who changed dosage or discontinued treatment early.
  • Main outcomes included assessing disease severity using the Eczema Area and Severity Index (EASI) and analyzing treatment responses, with results gathered from January to June 2022.
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Article Synopsis
  • The study explores how adolescents' multiple identities—national, heritage, and regional—impact their mental health, particularly regarding experiences of teacher discrimination.
  • It finds that regional identity is significant and not typically included in existing research, emphasizing the socio-political contexts of migration and integration.
  • Analysis of survey data reveals three identity profiles among students of Turkish and Moroccan descent: full integration, national integration, and (weak) separation, with nationally integrated youth showing lower levels of depression compared to fully integrated peers.
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With increasing immigration, it is increasingly important to understand whether and when children consider immigrant peers as co-nationals. Using an experimental design, we examined among native-born preadolescents (8-13 years of age) in the Netherlands whether and when they perceive immigrant peers as co-nationals. First, and in agreement with the social categorization account, we expected that the use of dual identity (vs single ethnic identity) labels for immigrant peers leads to stronger co-nationality perceptions and a related stronger desire for close social contact.

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Article Synopsis
  • A study was conducted to evaluate different dosing regimens of dupilumab for patients with controlled atopic dermatitis (AD), using a patient-centered approach, as no real-world studies existed on this topic.
  • Ninety adult patients were divided into three groups based on their dupilumab dosing frequency, with results showing that disease severity scores remained stable despite changes in dosing intervals.
  • Although some patients experienced a temporary increase in pruritus (itching), overall biomarkers and dupilumab serum levels indicated that dose reduction could be effective while maintaining low disease activity for those with controlled AD.
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Objective: Although patients with vascular diseases often face multiple treatment options with different risks and benefits, the application of shared decision making (SDM) remains low. In SDM, clinicians and their patients work together to decide upon the treatment option that best fits the patient's situation and preference. This study aimed to reveal predictors of the extent to which the SDM process occurs in vascular surgery.

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This study identified risk factors for the development of dupilumab-associated ocular surface disease in patients with moderate-to-severe atopic dermatitis in a large prospective daily practice cohort. Data from the Dutch BioDay Registry were used to assess the risk of developing dupilumab-associated ocular surface disease, by performing univariate and multivariate logistic regression analyses. A total of 469 patients were included, of which 152/469 (32.

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Background: Despite the growing body of research concerning affective relationships between teachers and ethnic minority students, very little is known about student-teacher relationship (STR) quality for religious minority students. Many Islamic schools have a mixed workforce consisting of both Muslim and non-Muslim teachers. This means that the quality of religiously congruent and religiously incongruent STRs can be directly compared.

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Dupilumab treatment improves signs, symptoms, and quality of life in patients with moderate-to-severe atopic dermatitis. This study evaluated the impact of dupilumab treatment on absenteeism, presenteeism, and related costs in a large multi-centre cohort of adult patients with difficult-to-treat atopic dermatitis in daily practice. Patients treated with dupilumab participating in the Dutch BioDay Registry reporting employment were included.

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Dermal fibroblasts are strategically positioned underneath the basal epidermis layer to support keratinocyte proliferation and extracellular matrix production. In inflammatory conditions, these fibroblasts produce cytokines and chemokines that promote the chemoattraction of immune cells into the dermis and the hyperplasia of the epidermis, two characteristic hallmarks of psoriasis. However, how dermal fibroblasts specifically contribute to psoriasis development remains largely uncharacterized.

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