Publications by authors named "Thieu Hoang LE"
Background: Vietnam continues to have measles and rubella outbreaks following supplementary immunization activities (SIA) and routine immunization despite both having high reported coverage. To evaluate immunization activities, age-specific immunity against measles and rubella, and the number of averted Congenital Rubella Syndrome (CRS) cases, must be estimated.
Methods: Dried blood spots were collected from 2091 randomly selected individuals aged 1-39 years.
Article Synopsis
- Vietnam's 3-dose hepatitis B immunization program shows positive effects on reducing chronic HBV prevalence, particularly in the age group of 20-39 compared to younger populations.
- The study utilized a four-stage cluster sampling method and rapid testing to assess HBsAg positivity, finding significant decreases in prevalence post-vaccine implementation, except for a notable increase in certain birth cohorts during vaccine shortages.
- Overall, the evaluation highlights the effectiveness of the HBV vaccination policy in Vietnam, emphasizing the need for monitoring birth dosing and immunization coverage to maintain progress.
Comparison between a rapid diagnostic test and dried blood spot-based immunoassay for hepatitis B surface antigen testing: Performance and cost implications in a population-based serosurvey in Vietnam.
Int J Infect Dis
December 2022
Objectives: This study aimed to determine the agreement between a rapid diagnostic test (RDT) and a dried blood spot (DBS)-based electrochemiluminescence immunoassay (ECLIA) of hepatitis B surface antigen and to compare the costs of conducting serosurveys using RDTs and DBS in a field setting.
Methods: A serosurvey was conducted in the South Central Coast region of Vietnam in May 2019. Participants aged 1-39 years were recruited using a four-stage random sampling method and tested for hepatitis B surface antigen using an RDT kit (Alere Determine) and a DBS-based ECLIA.