Using appropriate wound dressings is crucial when treating burn wounds to promote accelerated healing. Sodium alginate (SA)-based gels containing Carboxymethyl cellulose (CMC) and Pluronic F127 were prepared. The formulations.
View Article and Find Full Text PDFInt J Med Mushrooms
August 2024
Antifungal and antibacterial activities of crude extracts of Phellinus extensus, Ph. gilvus, Ph. pachyphloeus, Ph.
View Article and Find Full Text PDFThe efficacy of 23 bacterial isolates obtained from surface-sterilized stems and leaves of three medicinal plants ( Miller, , and ) was investigated in an endeavour to prevent the growth of using the cross-streak method. Endophytes were isolated by incubating sterile plant materials on nutrient agar at 30 °C for 5 days. Two isolates showing activity were subsequently utilized to produce the extracts.
View Article and Find Full Text PDFBackground: Resistance to antimicrobial drugs as a result of prolonged use usually results in clinical failure, especially in wound infections. Development of effective antimicrobial therapeutics for the management of infected wounds from a natural source with improved therapeutic effects is a pressing need.
Objective: In this study, carbopol-mastic gum-based topical gels were loaded with silver nanoparticles in combination with either neem bark extract or carvacrol oil.
The current study is focused on the development of water-soluble wound dressings, which are potential dressings for the treatment of burn wounds. Sodium alginate-based dissolvable wound dressings were prepared and loaded with silver nanoparticles and various antibiotics (ampicillin and ciprofloxacin) followed by characterization and antibacterial studies. The prepared sodium alginate-based dissolvable wound dressing exhibited good porosity, water uptake and moisture content, promising antibacterial activity, high absorption capacity of simulated wound exudates, excellent water vapor transmission rate in the range of 2000 to 5000 g/m day, sustained drug-release profiles and water solubility.
View Article and Find Full Text PDFThis study reports on the spectroscopic characterization and antimicrobial potency of polyurethane cyclodextrin co-polymerized phosphorylated multiwalled carbon nanotube-doped Ag-TiO nanoparticle (pMWCNT-CD/Ag-TiO) bionanosponge nanocomposite. The synthesis of pMWCNT-CD/Ag-TiO bionanosponge nanocomposite was carried out through the combined processes of amidation and polymerization reactions as well as the sol-gel method. The native nanosponge cyclodextrin and phosphorylated multiwalled carbon nanotube-nanosponge CD (pMWCNT-CD) polyurethanes were also prepared, and their antimicrobial activities carried out for comparison purposes.
View Article and Find Full Text PDFInt J Med Mushrooms
February 2021
Antifungal and antibacterial activities of crude extracts of carpophore compared with those of sclerotium of Pleurotus tuber-regium were investigated on 11 species of bacterial and 3 fungal human pathogens. The minimal inhibitory concentration (MIC) of carpophore extract was recorded to be 12.5 mg/mL on Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, Escherichia cloacae, Proteus mirabilis, P.
View Article and Find Full Text PDFA series of Schiff bases (-) bearing benzimidazole moiety was successfully synthesized in ethanol by refluxing Oct-2-ynoic acid (1,3-dihydrobenzimidazole-2-ylidene)amide with substituted amines. Fourier transform infrared (FTIR), ultra violet light (UV-VIS), elemental analysis, proton (H) and carbon (C) nuclear magnetic resonance spectroscopy were used to characterize the newly synthesized Schiff bases. Micro dilution method was used to determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of the Schiff bases, against 14 human pathogenic bacteria (8 Gram negative and 6 Gram positive) and against 7 fungal strains (5 and 2 ) representatives.
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