Background: Critically ill patients are at high risk of multiple organ failure syndrome (MODS) and gastrointestinal (GI) injury and dysfunction, which are associated with increased mortality rates. The acute gastrointestinal injury (AGI) scale has shown promise in assessing GI dysfunction. However, the combined utility of AGI with established disease severity scores remains unclear.
View Article and Find Full Text PDFObjectives: To evaluate the effectiveness of resin infiltration in improving the aesthetic appearance of anterior teeth affected by molar-incisor hypomineralisation (MIH).
Data Sources: PubMed, Scopus, EMBASE, Web of Science, ScienceDirect, and Cochrane Central Register of Controlled Trials (CENTRAL) were searched from 2009 to 2024. The protocol was registered in the International Prospective Database of Systematic Reviews (PROSPERO CRD42023461909).
Three new dihydrophenanthrenes were isolated from the whole plant of collected in Vietnam. These compounds were identified as 2,3,5-trihydroxy-9,10-dihydrophenanthrene (), 2-methoxy-5-hydroxy-9,10-dihydrophenanthrene 3-O--D-glucopyranoside (), and 2,5-dihydroxy-9,10-dihydrophenanthrene 3-O--D-glucopyranoside (). Their structures were determined by HR-ESI-MS and 1D, 2D NMR spectroscopy.
View Article and Find Full Text PDFFirst reported in August 2022, the Langya virus (LayV) has emerged as a potential global health threat in the post-COVID-19 era. Preliminary reports show that 35 patients near Shandong and Henan, China experienced a febrile acute LayV infection. We conducted this review following the PRISMA protocol to synthesise current knowledge on LayV's characteristics in terms of molecular, clinical, and public health perspectives.
View Article and Find Full Text PDFCellulose nanocrystals are commonly obtained by acid hydrolysis, particularly with HSO. However, a small amount of deposited sulfate-groups contributes to the degradation of their thermal stability. This study prepared thermally-stable and sulfate-group-free cellulose nanospheres (CNSs) from office waste paper by HSO hydrolysis followed by solvolytic desulfation.
View Article and Find Full Text PDFThis study synthesized cellulose-g-poly(acrylic acid) with high water absorbency using the cellulose extracted from pineapple leaves. The synthesis experiment used a novel combination of ethylene glycol dimethacrylate (EGDMA) and azobisisobutyronitrile (AIBN) as the cross-linker and the initiator, respectively. Experimental results showed that the concentrations of AIBN and EGDMA had significant effects on the structure and the water absorbency of the cross-linked materials.
View Article and Find Full Text PDFIntroduction: Leiomyomatosis peritonealis disseminata (LPD) is a rare disease that can be challenging to diagnose. In this report, we present a case of LPD arising 5 years after laparoscopic uterine myomectomy using a power morcellator.
Presentation Of Case: A 32-year-old woman was admitted to our hospital with complaints of vaginal bleeding and abdominal discomfort.
Reinvestigation of a methanol extract of afforded a new 3- hydroxyisoflavanone, 3,5,7,2',4'-pentahydroxyisoflavanone (), two new monoaryl glucosides, 3,4-dimethoxyphenyl 1--(6'--acetyl)--D-glucopyranoside ( and 3,4,5-trimethoxyphenyl 1--(6'--acetyl)--D-glucopyranoside (), in addition to three known compounds, 3'--methylorobol (), robusflavone B (), and apigenin (). The structural elucidation of these compounds was achieved by analyses of their spectroscopic data (HR-ESI-MS, 1 D- and 2 D-NMR) and acidic hydrolysis. The extracts and compounds - exhibited weak or no cytotoxic activity against KB, HepG2, Lu and MCF7 cell lines.
View Article and Find Full Text PDFMethylotrophs, which can utilize methanol as a sole carbon source, are promising microorganisms to be exploited in a methanol-based bioeconomy, in which a variety of useful compounds are biotechnologically produced from natural gas-derived methanol. Pink-pigmented facultative methylotrophs (PPFMs) are common plant phyllospheric bacteria and are known to enhance seedling growth and total biomass of various plants. However, improvement of crop yield by inoculation of PPFMs at the field level has not been well investigated.
View Article and Find Full Text PDFWe previously reported the inhibitory potentials of momilactones A (MA) and B (MB) against key enzymes related to type 2 diabetes and obesity. In this study, antioxidant and anti-skin-aging activities of MA and MB were investigated and compared with tricin, a well-known antioxidant and antiaging flavonoid in rice. MA, MB, and tricin were purified from rice husk by column chromatography and their biological activities were subsequently assayed by in vitro trials.
View Article and Find Full Text PDFPhytochemical investigation and chromatographic separation of extracts from the aerial parts of (L.) DC. (synonym Lam.
View Article and Find Full Text PDFA new isoflavanone, (3)-5,7-dihydroxy-2',3',4'-trimethoxy-6,5'-diprenylisoflavanone () and eight known compounds including five flavones (), two triterpenes () and a steroid () were isolated from the whole plant of (Leguminosae). The structure of was elucidated by detailed spectroscopic means including IR, HR-ESI-MS, 1D and 2D NMR, and CD data. Compounds were evaluated for their cytotoxicity against four human cancer cell lines KB (mouth epidermal carcinoma), HepG2 (hepatocellular carcinoma), Lu (lung carcinoma) and MCF7 (breast carcinoma).
View Article and Find Full Text PDFRepeated column chromatography of the n-hexane extract of leaves (Moraceae) led to isolation of a new oleanane triterpene, 3-hydroxy-11-oxo-olean-12-enyl-3-stearate () in addition to three known compounds, taraxerol (), 3-acetoxy-11-methoxy-12-ursene () and 3-acetoxy-11-hydroxy-12-ursene (). Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literatures.
View Article and Find Full Text PDFA new diterpene, cassipouryl hexadecanoate (), in addition to the cassipourol () and four terpenes () were isolated from the twigs and leaves of (Blume) de Laub. The structures of the two monocyclic diterpenes (, ), were elucidated on the basic of 1D and 2D NMR spectroscopic data and compared with the literature. These two monocyclic diterpenes (, ) were tested for their anti-proliferative activity on acute myeloid leukemia (OCI-AML) cells.
View Article and Find Full Text PDFThis study describes the chemical constituents of Oldenlandia pinifolia (Wall. Ex G. Don) Kuntze (synonym Hedyotis pinifolia Wall.
View Article and Find Full Text PDFA phytochemical study of n-hexane and ethyl acetate extracts of Pinus dalatensis Ferré leaves led to the isolation of 11 compounds, including one caryolane sesquiterpenoid (1), five labdane diterpenoids (2, 3, 4, 5, 6), one serratane triterpenoid (7), one diacylated flavonoid glucoside (8), one stilbenoid (9) and two sterols (10, 11). The structural characterisation of the isolated compounds was elucidated by spectroscopic data and comparison with the literature report on the chemical constituents from Pinus dalatensis Ferré. Futhermore, three compounds 1, 4 and 6 were obtained for the first time from the genus Pinus.
View Article and Find Full Text PDFUnlabelled: Acute myocardial infarction (MI) caused by ischemia is the most common cause of cardiac dysfunction. While growth factor therapy is promising, the retention in the highly vascularized myocardium is limited and prevents sustained activation needed for adequate cellular responses. Here, we demonstrated the use of polyethylene glycol-fibrinogen (PF) hydrogels for sustained dual delivery of vascular endothelial growth factor (VEGF) and angiopoietin-1 (ANG-1) to enhance myocardial repair and function.
View Article and Find Full Text PDFThe HIV/AIDS epidemic in Vietnam is concentrated in subgroups of the population, including men who have sex with men (MSM). Pre-exposure prophylaxis (PrEP) is a viable strategy for HIV prevention, but knowledge about and preferences for PrEP delivery among Vietnamese MSM are not well understood. In 2015, an online survey was conducted with recruitment via social networking websites for MSM and peer recruitment.
View Article and Find Full Text PDFGlobally, transgender women have higher risk for HIV than the general population and men who have sex with men, but there is little data on this population in Vietnam. In 2015 we conducted a biological and behavioral survey of 205 transgender women in Ho Chi Minh City, Vietnam. Factors associated with HIV and syphilis infection were assessed through multivariable logistic regression models.
View Article and Find Full Text PDFFew studies have considered acceptability of HIV pre-exposure prophylaxis (PrEP) among transgender women in Southeast Asia. We assessed PrEP indications and readiness among a sample of HIV-uninfected transgender women in Ho Chi Minh City, Vietnam. Of 168 HIV-uninfected transgender women, 72.
View Article and Find Full Text PDFObjective: To investigate the antitumor effect of maesopsin 4-O-β-glucoside (TAT2) isolated from the leaves of Artocarpus tonkinensis (A. tonkinensis) A. Chev.
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